Propene

Propene

SCHEMBL3210862

C=CC.O=C(OO)c1ccccc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 5/20 0.54
▸ LMNA P02545 2/20 0.52
▸ F2 P00734 1/20 0.52
▸ AKT1 P31749 1/20 0.48
▸ TDP1 Q9NUW8 5/20 0.46
▸ KMT2A Q03164 4/20 0.46
▸ MAPT P10636 3/20 0.46
▸ ALDH1A1 P00352 3/20 0.46
▸ HSD17B10 Q99714 2/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ PLA2G7 Q13093 2/20 0.45
▸ SLC6A3 Q01959 2/20 0.44
▸ TP53 P04637 1/20 0.44
▸ POLB P06746 2/20 0.43
▸ CYP3A4 P08684 2/20 0.43
▸ L3MBTL1 Q9Y468 2/20 0.43
▸ PARP1 P09874 1/20 0.43
▸ CYP2C19 P33261 1/20 0.43
▸ RECQL P46063 1/20 0.43
▸ BLM P54132 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL11292486 0.88 AKT1 (0.54) TSHRLMNAF2AKT1TDP1
Ethane SCHEMBL455951 0.87 TSHR (0.62) TSHRLMNAF2TDP1KMT2A
Ethylene SCHEMBL1835188 0.87 LMNA (0.61) TSHRLMNAF2TDP1KMT2A
Hydrogen Peroxide SCHEMBL11489043 0.87 LMNA (0.67) TSHRLMNAF2TDP1KMT2A
Benzene SCHEMBL10686034 0.87 LMNA (0.67) TSHRLMNAF2TDP1KMT2A
SCHEMBL27265493 0.87 LMNA (0.67) TSHRLMNAF2TDP1KMT2A
SCHEMBL1816 0.87 LMNA (0.67) TSHRLMNAF2TDP1KMT2A
Hydrogen Peroxide SCHEMBL2929887 0.87 LMNA (0.67) TSHRLMNAF2TDP1KMT2A
SCHEMBL30688231 0.85 TSHR (0.56) TSHRLMNAF2TDP1KMT2A
Benzoyl Peroxide SCHEMBL28195815 0.85 LMNA (0.74) TSHRLMNAF2AKT1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3246048-B1 BI-FUNCTIONAL CO-POLYMER USE FOR OPHTHALMIC APPLICATIONS CALM WATER THERAPEUTICS LLC (US) 2024-04-03 — — EP disclosed
US-20230355661-A1 BI-FUNCTIONAL CO-POLYMER USE FOR OPHTHALMIC AND OTHER TOPICAL AND LOCAL APPLICATIONS CALM WATER THERAPEUTICS LLC 2023-11-09 — — US disclosed
US-20230201251-A1 METHODS FOR USING BIOADHESIVE AND STERIC INTERACTIONS OF COPOLYMERS WITH AT LEAST TWO MOIETIES TO MINIMIZE ADVERSE EFFECTS MEDIATED BY EXTERNAL INFLUENCES ON CELL, TISSUE, ORGAN SYSTEM, AND ORGANISM BIOLOGY CALM WATER THERAPEUTICS LLC 2023-06-29 — — US disclosed
WO-2023081891-A2 METHODS FOR USING BIOADHESIVE AND STERIC INTERACTIONS OF COPOLYMERS WITH AT LEAST TWO MOIETIES TO MINIMIZE ADVERSE EFFECTS MEDIATED BY EXTERNAL INFLUENCES ON CELL, TISSUE, ORGAN SYSTEM, AND ORGANISM BIOLOGY CALM WATER THERAPEUTICS LLC (US) 2023-05-11 — — WO disclosed
EP-4145997-A1 METHODS FOR USING BIOADHESIVE AND STERIC INTERACTIONS OF COPOLYMERS WITH AT LEAST TWO MOIETIES TO MINIMIZE ADVERSE EFFECTS MEDIATED BY EXTERNAL INFLUENCES ON CELL, TISSUE, ORGAN SYSTEM, AND ORGANISM BIOLOGY Calm Water Therapeutics LLC (US) 2023-03-15 — — EP disclosed
US-20220023334-A1 BI-FUNCTIONAL CO-POLYMER USE FOR OPHTHALMIC AND OTHER TOPICAL AND LOCAL APPLICATIONS CALM WATER THERAPEUTICS LLC (US) 2022-01-27 — — US disclosed
US-20210393672-A1 BI-FUNCTIONAL CO-POLYMER USE FOR OPHTHALMIC AND OTHER TOPICAL AND LOCAL APPLICATIONS CALM WATER THERAPEUTICS LLC (US) 2021-12-23 — — US disclosed
WO-2021226441-A1 METHODS FOR USING BIOADHESIVE AND STERIC INTERACTIONS OF COPOLYMERS WITH AT LEAST TWO MOIETIES TO MINIMIZE ADVERSE EFFECTS MEDIATED BY EXTERNAL INFLUENCES ON CELL, TISSUE, ORGAN SYSTEM, AND ORGANISM BIOLOGY CALM WATER THERAPEUTICS LLC (US) 2021-11-11 — — WO disclosed
US-11135242-B2 Bi-functional co-polymer use for ophthalmic and other topical and local applications CALM WATER THERAPEUTICS LLC (US) 2021-10-05 — — US disclosed
US-11110119-B2 Bi-functional co-polymer use for ophthalmic and other topical and local applications CALM WATER THERAPEUTICS LLC (US) 2021-09-07 — — US disclosed
US-9295693-B2 Bi-functional co-polymer use for ophthalmic and other topical and local applications EYEON PARTICLE SCIENCES LLC (US) 2016-03-29 — — US disclosed
US-9283248-B2 Bi-functional co-polymer use for ophthalmic and other topical and local applications EYEON PARTICLE SCIENCES LLC (US) 2016-03-15 — — US disclosed
US-20150190422-A1 Bi-Functional Co-Polymer Use for Ophthalmic and Other Topical and Local Applications CALM WATER THERAPEUTICS LLC 2015-07-09 — — US disclosed
US-9005596-B2 Bi-functional co-polymer use for ophthalmic and other topical and local applications EYEON PARTICLE SCIENCES LLC (US) 2015-04-14 — — US disclosed
US-20140341967-A1 Bi-Functional Co-Polymer Use for Ophthalmic and Other Topical and Local Applications CALM WATER THERAPEUTICS LLC 2014-11-20 — — US disclosed
US-20140322157-A1 Bi-Functional Co-Polymer Use for Ophthalmic and Other Topical and Local Applications CALM WATER THERAPEUTICS LLC 2014-10-30 — — US disclosed
US-8802075-B2 Bi-functional co-polymer use for opthalmic and other topical and local applications EYEON PARTICLE SCIENCES LLC (US) 2014-08-12 — — US disclosed
CN-102549129-A Trunk piston engine lubricating oil compositions CHEVRON ORONITE TECHNOLOGY BV 2012-07-04 — — CN disclosed
US-20100226963-A1 BI-FUNCTIONAL CO-POLYMER USE FOR OPTHALMIC AND OTHER TOPICAL AND LOCAL APPLICATIONS EYEON PARTICLE SCIENCES LLC (US) 2010-09-09 — — US disclosed
WO-2010096558-A1 BI-FUNCTIONAL CO-POLYMER USE FOR OPHTHALMIC AND OTHER TOPICAL AND LOCAL APPLICATIONS EYEON PARTICLE SCIENCES LLC (US) 2010-08-26 — — WO disclosed
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