SCHEMBL3211204

SCHEMBL3211204

CC(N)N1C(=O)c2ccccc2C1=O

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.53
LMNA P02545 2/20 0.52
CASP3 P42574 1/20 0.48
ALDH1A1 P00352 5/20 0.46
HTT P42858 2/20 0.46
NPC1 O15118 1/20 0.45
TP53 P04637 1/20 0.45
GAA P10253 2/20 0.44
ELANE P08246 1/20 0.44
KMT2A Q03164 1/20 0.44
POLB P06746 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MAPT P10636 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15081352 0.83 TDP1 (0.50) TDP1LMNACASP3ALDH1A1HTT
SCHEMBL6656473 0.81 TDP1 (0.57) TDP1LMNACASP3ALDH1A1HTT
SCHEMBL29381145 0.81 TDP1 (0.57) TDP1LMNACASP3ALDH1A1HTT
SCHEMBL166122 0.81 TDP1 (0.57) TDP1LMNACASP3ALDH1A1HTT
Hydrochloric Acid SCHEMBL11212342 0.81 TDP1 (0.49) TDP1LMNACASP3ALDH1A1HTT
SCHEMBL5398167 0.79 TDP1 (0.51) TDP1LMNACASP3ALDH1A1HTT
SCHEMBL5398133 0.79 TDP1 (0.51) TDP1LMNACASP3ALDH1A1HTT
SCHEMBL1892274 0.79 TDP1 (0.55) TDP1LMNACASP3ALDH1A1HTT
SCHEMBL11229719 0.77 TDP1 (0.53) TDP1LMNACASP3ALDH1A1HTT
SCHEMBL22795141 0.77 TDP1 (0.53) TDP1LMNACASP3ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4643883-A2 ANTIBODY-DRUG CONJUGATE CONTAINING N-METHYLENE AMIDE LINKER Hangzhou Adcoris Biopharma Co., Ltd (CN) 2025-11-05 EP disclosed
WO-2024140433-A2 ANTIBODY-DRUG CONJUGATE CONTAINING N-METHYLENE AMIDE LINKER 杭州爱科瑞思生物医药有限公司 2024-07-04 WO disclosed
CN-116712561-A Antibody-drug conjugates containing an N-methyleneamide linker 杭州爱科瑞思生物医药有限公司 2023-09-08 CN disclosed
CN-114806283-A White pigment dispersion and composition for forming white partition wall containing same 山阳色素株式会社 2022-07-29 CN disclosed
US-8048966-B2 Use of a kinked rigid-rod polyarylene SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2011-11-01 US disclosed
US-20110263729-A1 Fiber or Foil from Polymers with High Tg and Process for their Manufacture SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2011-10-27 US disclosed
US-20110046292-A1 NEW USE OF A KINKED RIGID-ROD POLYARYLENE SOLVAY ADVANCED POLYMERS L.L.C. (US) 2011-02-24 US disclosed
US-7875696-B2 improved fire resistance; films SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2011-01-25 US disclosed
US-7678850-B2 Pigment dispersions containing aminated acrylic macromonomer dispersant E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-03-16 US disclosed
US-20090234077-A1 New use of a kinked rigid-rod polyarylene, and articles made from said kinked rigid-rod polyarylene SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2009-09-17 US disclosed
US-20090124767-A1 Sulfone Polymer Composition SOLVAY ADVANCED POLYMERS L.L.C. (US) 2009-05-14 US disclosed
US-20090069507-A1 Aromatic Polyimide Composition SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2009-03-12 US disclosed
US-20090026128-A1 High Performance Shaped Articles, Methods Of Making, And Uses Thereof SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2009-01-29 US disclosed
US-20090012231-A1 PIGMENT DISPERSIONS CONTAINING AMINATED ACRYLIC MACROMONOMER DISPERSANT E. I. DU PONT DE NEMOURS AND COMPANY 2009-01-08 US disclosed
EP-1966335-A2 PIGMENT DISPERSIONS CONTAINING AMINATED ACRYLIC MACROMONOMER DISPERSANT E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-09-10 EP disclosed
US-20070276100-A1 Electronic Components SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2007-11-29 US disclosed
WO-2007070724-A2 PIGMENT DISPERSIONS CONTAINING AMINATED ACRYLIC MACROMONOMER DISPERSANT E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-06-21 WO disclosed
US-20070142546-A1 Pigment dispersions containing aminated acrylic macromonomer dispersant AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) 2007-06-21 US disclosed