Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166122 | 0.85 | TDP1 (0.57) | TDP1LMNACASP3ALDH1A1HTT | |
| SCHEMBL29381145 | 0.85 | TDP1 (0.57) | TDP1LMNACASP3ALDH1A1HTT | |
| SCHEMBL1892274 | 0.83 | TDP1 (0.55) | TDP1LMNACASP3ALDH1A1HTT | |
| SCHEMBL3211204 | 0.81 | TDP1 (0.53) | TDP1LMNACASP3ALDH1A1HTT | |
| SCHEMBL4197298 | 0.81 | LMNA (0.56) | TDP1LMNACASP3ALDH1A1HTT | |
| SCHEMBL16169017 | 0.81 | TDP1 (0.53) | TDP1LMNACASP3ALDH1A1HTT | |
| SCHEMBL19981234 | 0.81 | TDP1 (0.53) | TDP1LMNACASP3ALDH1A1HTT | |
| SCHEMBL11229719 | 0.81 | TDP1 (0.53) | TDP1LMNACASP3ALDH1A1HTT | |
| SCHEMBL22795141 | 0.81 | TDP1 (0.53) | TDP1LMNACASP3ALDH1A1HTT | |
| SCHEMBL9815347 | 0.81 | TDP1 (0.53) | TDP1LMNACASP3ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| US-8362114-B2 | Thermoplastic compositions containing microspheres | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2013-01-29 | — | — | US | disclosed |
| US-20130012634-A1 | Polymer compositions comprising core/shell particles | SOLVAY SA (BE) | 2013-01-10 | — | — | US | disclosed |
| US-8048966-B2 | Use of a kinked rigid-rod polyarylene | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2011-11-01 | — | — | US | disclosed |
| US-20110263729-A1 | Fiber or Foil from Polymers with High Tg and Process for their Manufacture | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2011-10-27 | — | — | US | disclosed |
| WO-2011117410-A1 | POLYMER COMPOSITIONS COMPRISING CORE/SHELL PARTICLES | SOLVAY SA (BE) | 2011-09-29 | — | — | WO | disclosed |
| US-20110071237-A1 | Flame Resistance Natural Fiber-Filled Thermoplastics with Improved Properties | CHEMTURA CORPORATION (US) | 2011-03-24 | — | — | US | disclosed |
| US-20110046292-A1 | NEW USE OF A KINKED RIGID-ROD POLYARYLENE | SOLVAY ADVANCED POLYMERS L.L.C. (US) | 2011-02-24 | — | — | US | disclosed |
| US-7875696-B2 | improved fire resistance; films | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2011-01-25 | — | — | US | disclosed |
| US-20100324171-A1 | Thermoplastic compositions containing microspheres | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2010-12-23 | — | — | US | disclosed |
| US-20080255309-A1 | High-Performance Polysulfone Composition | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2008-10-16 | — | — | US | disclosed |
| US-20080234440-A1 | High-Performance Poly(Aryl Ether Sulfone) Composition | SOLVAY ADVANCED PLOYMERS, L.L.C. (US) | 2008-09-25 | — | — | US | disclosed |
| US-20080073627-A1 | Flame resistance natural fiber-filled thermoplastics with improved properties | WEBER CITY ROAD LLC | 2008-03-27 | — | — | US | disclosed |
| US-20070276100-A1 | Electronic Components | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2007-11-29 | — | — | US | disclosed |
| US-20040176612-A1 | Method for preparing n-($g(v)-bromoalkyl)phthalimides | GILLET JEAN-PHILIPPE (FR) | 2004-09-09 | — | — | US | disclosed |
| US-20040176613-A1 | Method for preparing n-($g(v)-bromoalkyl)phthalimides | GILLET JEAN-PHILIPPE (FR) | 2004-09-09 | — | — | US | disclosed |
| EP-1436261-A1 | METHOD FOR PREPARING N-($G(V)-BROMOALKYL)PHTHALIMIDES | Albemarle Chemicals SAS (US) | 2004-07-14 | — | — | EP | disclosed |
| EP-1436260-A1 | METHOD FOR PREPARING N-(V)-BROMOALKYL)PHTHALIMIDES | Albemarle Chemicals SAS (US) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003027070-A1 | METHOD FOR PREPARING N-($G(V)-BROMOALKYL)PHTHALIMIDES | ALBEMARLE CHEMICALS SAS (US) | 2003-04-03 | — | — | WO | disclosed |
| WO-2003027071-A1 | METHOD FOR PREPARING N-($G(V)-BROMOALKYL)PHTHALIMIDES | ALBEMARLE CHEMICALS SAS (US) | 2003-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176612-A1 | Method for preparing n-($g(v)-bromoalkyl)phthalimides | GK, DGKA, GNG2 | TDP1 3482/4885LMNA 536/4885CASP3 2150/4885 |
| US-20040176613-A1 | Method for preparing n-($g(v)-bromoalkyl)phthalimides | GK, DGKG, DGKA | TDP1 3495/4885LMNA 604/4885CASP3 1326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.