Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3211274 | 0.82 | GAA (0.38) | SMN1; SMN2ALDH1A1MAPK1MAPTPOLB | |
| SCHEMBL6030456 | 0.79 | MEN1 (0.39) | SMN1; SMN2ALDH1A1MAPK1MAPTPOLB | |
| SCHEMBL6030958 | 0.78 | MAPK1 (0.37) | SMN1; SMN2ALDH1A1MAPK1MAPTPOLB | |
| SCHEMBL7081843 | 0.77 | TAAR1 (0.41) | SMN1; SMN2ALDH1A1MAPK1MAPTPOLB | |
| SCHEMBL26608490 | 0.71 | POLB (0.54) | SMN1; SMN2ALDH1A1MAPK1MAPTPOLB | |
| SCHEMBL5746291 | 0.71 | LMNA (0.44) | MAPTGAARXFP1 | |
| SCHEMBL2436948 | 0.69 | GRM1 (0.45) | SMN1; SMN2ALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL22558695 | 0.69 | NPC1 (0.53) | SMN1; SMN2ALDH1A1MAPTPOLBGAA | |
| SCHEMBL29235222 | 0.68 | KMT2A (0.55) | SMN1; SMN2MAPK1MAPTKMT2ANPC1 | |
| SCHEMBL31026874 | 0.68 | KMT2A (0.55) | SMN1; SMN2MAPK1MAPTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048700-A1 | LIQUID FORMULATION OF PYRETHROIDS | BAYER CROPSCIENCE AG (DE) | 2010-02-25 | — | — | US | disclosed |
| EP-2099748-A1 | INSECTICIDAL BENZAMIDINES | Bayer CropScience Aktiengesellschaft (DE) | 2009-09-16 | — | — | EP | disclosed |
| WO-2007131680-A1 | INSECTICIDAL BENZAMIDINES | BAYER CROPSCIENCE AG (DE) | 2007-11-22 | — | — | WO | disclosed |