SCHEMBL3211316

SCHEMBL3211316

O=C(Cl)C1CC2CCC1O2

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SLC6A4 P31645 4/20 0.36
SLC6A3 Q01959 4/20 0.36
RIPK1 Q13546 3/20 0.35
KDM4E B2RXH2 1/20 0.34
GMNN O75496 1/20 0.34
LMNA P02545 1/20 0.34
PMP22 Q01453 1/20 0.34
TFPI2 P48307 1/20 0.34
TP53 P04637 1/20 0.34
TSHR P16473 1/20 0.34
NFKB1 P19838 1/20 0.34
THPO P40225 1/20 0.34
PSMB8 P28062 3/20 0.33
PSMB5 P28074 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34461967 0.82 KDM4E (0.44) MEN1KMT2ASLC6A4SLC6A3RIPK1
SCHEMBL8246038 0.82 KDM4E (0.44) MEN1KMT2ASLC6A4SLC6A3RIPK1
SCHEMBL3465697 0.82 KDM4E (0.44) MEN1KMT2ASLC6A4SLC6A3RIPK1
SCHEMBL8067270 0.82 KDM4E (0.44) MEN1KMT2ASLC6A4SLC6A3RIPK1
SCHEMBL3259183 0.82 KDM4E (0.44) MEN1KMT2ASLC6A4SLC6A3RIPK1
SCHEMBL9376106 0.82 KDM4E (0.44) MEN1KMT2ASLC6A4SLC6A3RIPK1
SCHEMBL4738727 0.82 KDM4E (0.44) MEN1KMT2ASLC6A4SLC6A3RIPK1
SCHEMBL13795024 0.82 KDM4E (0.44) MEN1KMT2ASLC6A4SLC6A3RIPK1
SCHEMBL4738730 0.82 KDM4E (0.44) MEN1KMT2ASLC6A4SLC6A3RIPK1
SCHEMBL2969767 0.82 KDM4E (0.44) MEN1KMT2ASLC6A4SLC6A3RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530212-B2 Carbene precursor compound for producing an adhesive surface on a substrate ISIS INNOVATION LIMITED (GB) 2013-09-10 US disclosed
EP-2054465-B1 TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION ISIS INNOVATION (GB) 2012-07-11 EP disclosed
US-20100068783-A1 TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION ISIS INNOVATION LIMITED (GB) 2010-03-18 US disclosed
EP-2054465-A1 TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION ISIS INNOVATION LIMITED (GB) 2009-05-06 EP disclosed
WO-2008023170-A1 TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION ISIS INNOVATION LIMITED (GB) 2008-02-28 WO disclosed
US-7261995-B2 Nitrogen-containing organic compound, chemically amplified resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-08-28 US disclosed
US-20050238993-A1 Nitrogen-containing organic compound, chemically amplified resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. 2005-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100068783-A1 TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION ITGB2, ITGA2B, ITGB1 MEN1 4361/4885KMT2A 1038/4885SLC6A4 4634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.