Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PPM1B | O75688 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8239877 | 1.00 | KDM4E (0.44) | KDM4EGMNNLMNAPMP22TFPI2 | |
| SCHEMBL13795024 | 1.00 | KDM4E (0.44) | KDM4EGMNNLMNAPMP22TFPI2 | |
| SCHEMBL3465697 | 1.00 | KDM4E (0.44) | KDM4EGMNNLMNAPMP22TFPI2 | |
| SCHEMBL34461967 | 1.00 | KDM4E (0.44) | KDM4EGMNNLMNAPMP22TFPI2 | |
| SCHEMBL3259183 | 1.00 | KDM4E (0.44) | KDM4EGMNNLMNAPMP22TFPI2 | |
| SCHEMBL9376106 | 1.00 | KDM4E (0.44) | KDM4EGMNNLMNAPMP22TFPI2 | |
| SCHEMBL4738730 | 1.00 | KDM4E (0.44) | KDM4EGMNNLMNAPMP22TFPI2 | |
| SCHEMBL8246038 | 1.00 | KDM4E (0.44) | KDM4EGMNNLMNAPMP22TFPI2 | |
| SCHEMBL8067270 | 1.00 | KDM4E (0.44) | KDM4EGMNNLMNAPMP22TFPI2 | |
| SCHEMBL4738727 | 1.00 | KDM4E (0.44) | KDM4EGMNNLMNAPMP22TFPI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110114349-B | Thiophene derivatives as antiviral agents | 埃尼奥制药公司 | 2022-03-15 | — | — | CN | claimed |
| WO-2008077809-A1 | PROCESS FOR THE MANUFACTURE OF 7-OXA-BICYCLO DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-07-03 | — | — | WO | claimed |
| US-20080154043-A1 | PROCESS FOR THE MANUFACTURE OF 7-OXA-BICYCLO DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-06-26 | — | — | US | claimed |
| US-12577234-B2 | Antagonists of the muscarinic acetylcholine receptor M4 | VANDERBILT UNIVERSITY (US) | 2026-03-17 | — | — | US | disclosed |
| EP-4612150-A1 | BRIDGED BICYCLIC HETEROCYCLOALKYL PYRIDO-[3,4-D]PYRIDAZINE AMINE DERIVATIVES USEFUL AS NLRP3 INHIBITORS | Ventus Therapeutics U.S., Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| US-20250257077-A1 | BRIDGED BICYCLIC HETEROCYCLOALKYL PYRIDO-[3,4-d]PYRIDAZINE AMINE DERIVATIVES USEFUL AS NLRP3 INHIBITORS | VENTUS THERAPEUTICS U.S., INC. | 2025-08-14 | — | — | US | disclosed |
| CN-115066428-B | Boric acid derivatives | 首药控股(北京)股份有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-119613408-A | Bicyclic ketone compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-110914271-B | Bicyclic ketone compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-118791500-A | 7-Oxabicyclo [2.2.1] heptane-2, 3-dicarboxylic acid derivative and preparation method and application thereof | 中国药科大学 | 2024-10-18 | — | — | CN | disclosed |
| US-20240300974-A1 | BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2024-09-12 | — | — | US | disclosed |
| US-20080154043-A1 | PROCESS FOR THE MANUFACTURE OF 7-OXA-BICYCLO DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-06-26 | — | — | US | disclosed |
| US-20080153030-A1 | Positive resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2008-06-26 | — | — | US | disclosed |
| WO-2008058342-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS | GENETIC TECHNOLOGIES LIMITED (AU) | 2008-05-22 | — | — | WO | disclosed |
| US-20070231738-A1 | Resist composition and patterning process using the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| WO-2007031557-A2 | ALCANOIC ACID AMIDES SUBSTITUTED BY SATURATED O-HETEROCYCLES | SPEEDEL EXPERIMENTA AG (CH) | 2007-03-22 | — | — | WO | disclosed |
| US-5641784-A | ADENOSINE ANTAGONISTS; TREATMENT OF NERVOUS SYSTEM DISORDERS, ALZHEIMER'S DISEASE | BOEHRINGER INGELHEIM KG (DE) | 1997-06-24 | — | — | US | disclosed |
| EP-0487673-A1 | NEW XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) | 1992-06-03 | — | — | EP | disclosed |
| WO-1992000297-A1 | NEW XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM KG (DE) | 1992-01-09 | — | — | WO | disclosed |
| US-4958036-A | Enantiomerically selective synthesis of certain N-substituted-2-(carbamyl 7-oxabicyclo[2.2.1]heptane-3-carboxylic acids | E. R. SQUIBB & SONS, INC. (US) | 1990-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250257077-A1 | BRIDGED BICYCLIC HETEROCYCLOALKYL PYRIDO-[3,4-d]PYRIDAZINE AMINE DERIVATIVES USEFUL AS NLRP3 INHIBITORS | NLRP3, NLRP1, NOD1 | KDM4E 2895/4885GMNN 4508/4885LMNA 1451/4885 |
| US-20080154043-A1 | PROCESS FOR THE MANUFACTURE OF 7-OXA-BICYCLO DERIVATIVES | CYP3A7, UGT2B7, CYP1B1 | KDM4E 1611/4885GMNN 2894/4885LMNA 2526/4885 |
| US-12577234-B2 | Antagonists of the muscarinic acetylcholine receptor M4 | CHRM3, CHRM4, CHRM2 | KDM4E 2168/4885GMNN 3300/4885LMNA 3873/4885 |
| US-20240300974-A1 | BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF | HSD17B7, CYP11B1, CYP11B2 | KDM4E 1229/4885GMNN 3901/4885LMNA 1111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.