Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.37 |
| ▸ | HTR2C | P28335 | 5/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1864062 | 0.87 | HTR2A (0.40) | HTR2AHTR2CNOTUMKMT2A | |
| SCHEMBL29851785 | 0.87 | HTR2A (0.40) | HTR2AHTR2CNOTUMKMT2A | |
| Hydroxyamine SCHEMBL9656520 | 0.82 | HTR2A (0.37) | HTR2AHTR2CNOTUMKMT2A | |
| SCHEMBL3203395 | 0.72 | HTR2A (0.35) | HTR2AHTR2CNOTUM | |
| SCHEMBL5253279 | 0.70 | DAO (0.40) | — | |
| SCHEMBL4860771 | 0.68 | HTR2A (0.30) | HTR2AHTR2C | |
| SCHEMBL29407762 | 0.67 | MKNK2 (0.30) | — | |
| SCHEMBL18229897 | 0.67 | HTR2A (0.49) | HTR2AHTR2CNOTUM | |
| SCHEMBL11009537 | 0.67 | NOTUM (0.38) | HTR2AHTR2CNOTUMKMT2A | |
| SCHEMBL2844837 | 0.65 | DAO (0.41) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790712-B2 | Substituted [1,4]diazepino[1,2-A]indoles and azepino[1,2-A]indoles as anti-cytokine inhibitors | BOEHRINGER INGELHEIM PHARMACEUTICAL, INC. (US) | 2010-09-07 | — | — | US | disclosed |