⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83314 | 1.00 | — | — | |
| SCHEMBL82149 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL9993578 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL11302777 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL29202607 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL12076441 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL12076346 | 0.97 | — | — | |
| SCHEMBL10582198 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL4741693 | 0.97 | — | — | |
| SCHEMBL82024 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117969421-A | Universal sensor and method for identifying absolute configuration and optical purity of beta-chiral primary amine | 中国医学科学院药物研究所 | 2024-05-03 | — | — | CN | claimed |
| CN-111574420-B | Preparation method of aminopyrrolidine | 北京石油化工学院 | 2022-09-20 | — | — | CN | claimed |
| CN-111574420-A | Preparation method of aminopyrrolidine | 北京石油化工学院 | 2020-08-25 | — | — | CN | claimed |
| US-20200115339-A1 | EFFLUX-PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | Basilea Pharmaceutica International AG (CH) | 2020-04-16 | — | — | US | claimed |
| US-10464896-B2 | Efflux-pump inhibitors and therapeutic uses thereof | Basilea Pharmaceutica International AG (CH) | 2019-11-05 | — | — | US | claimed |
| US-20180179158-A1 | EFFLUX-PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | Basilea Pharmaceutica International AG (CH) | 2018-06-28 | — | — | US | claimed |
| EP-3307725-A1 | EFFLUX-PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | Basilea Pharmaceutica International AG (CH) | 2018-04-18 | — | — | EP | claimed |
| WO-2017093157-A1 | PIPERIDINE, PYRROLIDINE AND 2-OXO-1,3-OXAZINANE DERIVATIVES AS INHIBITORS OF BACTERIAL EFFLUX-PUMPS FOR THE TREATMENT OF MICROBIAL INFECTIONS | BASILEA PHARMACEUTICA AG (CH) | 2017-06-08 | — | — | WO | claimed |
| WO-2016198691-A1 | EFFLUX-PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | BASILEA PHARMACEUTICA AG (CH) | 2016-12-15 | — | — | WO | claimed |
| CN-103097425-B | Process for preparing polyol mixtures | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-10-07 | — | — | CN | claimed |
| EP-1017358-A1 | REDUCTION OF HAIR GROWTH | THE GILLETTE COMPANY (US) | 2000-07-12 | — | — | EP | claimed |
| US-6056973-A | Therapeutic liposome composition and method of preparation | SEQUUS PHARMACEUTICALS, INC. (US) | 2000-05-02 | — | — | US | claimed |
| US-5939458-A | APPLYING AN INHIBITOR OF AMINOACYL-TRNA SYNTHETASE TO THE SKIN | GILLETTE COMPANY, THE | 1999-08-17 | — | — | US | claimed |
| WO-1999015136-A1 | REDUCTION OF HAIR GROWTH | THE GILLETTE COMPANY (US) | 1999-04-01 | — | — | WO | claimed |
| EP-0692470-A1 | Process for the preparation of optically active 1-substituted-2-(aminomethyl)pyrrolidine derivatives | Degussa Aktiengesellschaft (DE) | 1996-01-17 | — | — | EP | claimed |
| EP-0539281-A1 | New naphthamides, process for their preparation and their application in the therapeutical field | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1993-04-28 | — | — | EP | claimed |
| US-4950766-A | Preparation of benzamides useful as antiemetic agents | ERBAMONT, INC. (US) | 1990-08-21 | — | — | US | claimed |
| US-4948784-A | ANTICARCINOGENIC AND-TUMOR AGENTS; WATER-SOLUBEL MACROMOLICULAR COMPLEXES; SIDE EFFECT REDUCTION | KURARAY COMPANY, LTD. (JP) | 1990-08-14 | — | — | US | claimed |
| EP-0314483-A1 | Preparation of benzamides | ERBAMONT, INC. (US) | 1989-05-03 | — | — | EP | claimed |
| CN-86106163-A | New henzodiozepanne and synthetic method thereof and the application on therapeutics | — | 1987-04-08 | — | — | CN | claimed |