⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321167 | 1.00 | — | — | |
| SCHEMBL83314 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL9993578 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL11302777 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL29202607 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL12076441 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL12076346 | 0.97 | — | — | |
| SCHEMBL10582198 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL4741693 | 0.97 | — | — | |
| SCHEMBL82024 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 354 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117969421-A | Universal sensor and method for identifying absolute configuration and optical purity of beta-chiral primary amine | 中国医学科学院药物研究所 | 2024-05-03 | — | — | CN | claimed |
| US-8604051-B2 | Thieno-pyridine derivatives as MEK inhibitors | UCB PHARMA S.A. (BE) | 2013-12-10 | — | — | US | claimed |
| CN-102626655-B | Aldol reaction catalyst and preparation method and application thereof | UNIV SUN YAT SEN | 2013-07-31 | — | — | CN | claimed |
| US-20130150573-A1 | THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS | UCB PHARMA S.A. (BE) | 2013-06-13 | — | — | US | claimed |
| US-8394822-B2 | Thieno-pyridine derivatives as MEK inhibitors | UCB PHARMA, S.A. (BE) | 2013-03-12 | — | — | US | claimed |
| US-20120329774-A1 | THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS | UCB PHARMA S.A. (BE) | 2012-12-27 | — | — | US | claimed |
| US-8283359-B2 | Thieno-pyridine derivatives as MEK inhibitors | UCB PHARMA S.A. (BE) | 2012-10-09 | — | — | US | claimed |
| CN-102626655-A | Aldol reaction catalyst and preparation method and application thereof | UNIV SUN YAT SEN | 2012-08-08 | — | — | CN | claimed |
| US-20090264411-A1 | FUSED THIOPHENE DERIVATIVES AS MEK INHIBITORS | UCB PHARMA S.A. (BE) | 2009-10-22 | — | — | US | claimed |
| US-20090149437-A1 | THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS | UCB PHARMA S.A. (BE) | 2009-06-11 | — | — | US | claimed |
| WO-2004085436-A2 | PYRIDO[2,3-D]PYRIMIDIN-7-CARBOXYLIC ACID DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-10-07 | — | — | WO | claimed |
| US-20040191307-A1 | Therapeutic liposome composition and method of preparation | ALZA CORPORATION | 2004-09-30 | — | — | US | claimed |
| US-20040191250-A1 | Therapeutic liposome composition and method of preparation | ALZA CORPORATION | 2004-09-30 | — | — | US | claimed |
| US-20030215490-A1 | Therapeutic liposome composition and method of preparation | SEQUUS PHARMACEUTICALS, INC. | 2003-11-20 | — | — | US | claimed |
| US-6599902-B2 | For treating or preventing a protein kinase related disorder | SUGEN, INC. | 2003-07-29 | — | — | US | claimed |
| US-6316024-B1 | SELECTING LIPOSOME COMPRISING PRE-FORMED LIPOSOMES HAVING AN ENTRAPPED THERAPEUTIC AGENT; SELECTING TARGETING CONJUGATE COMPRISED OF LIPID HAVING A POLAR HEAD GROUP AND A HYDROPHOBIC TAIL, POLYMER, AND LIGAND; COMBINING | SEQUUS PHARMACEUTICALS, INC. | 2001-11-13 | — | — | US | claimed |
| US-20010038851-A1 | Therapeutic liposome composition and method of preparation | ALZA CORPORATION | 2001-11-08 | — | — | US | claimed |
| US-6056973-A | Therapeutic liposome composition and method of preparation | SEQUUS PHARMACEUTICALS, INC. (US) | 2000-05-02 | — | — | US | claimed |
| US-4950766-A | Preparation of benzamides useful as antiemetic agents | ERBAMONT, INC. (US) | 1990-08-21 | — | — | US | claimed |
| EP-0314483-A1 | Preparation of benzamides | ERBAMONT, INC. (US) | 1989-05-03 | — | — | EP | claimed |