⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491178 | 0.70 | — | — | |
| SCHEMBL246402 | 0.67 | — | — | |
| SCHEMBL603294 | 0.67 | — | — | |
| SCHEMBL6014450 | 0.67 | — | — | |
| SCHEMBL1261724 | 0.67 | — | — | |
| SCHEMBL77926 | 0.67 | — | — | |
| SCHEMBL606699 | 0.65 | — | — | |
| SCHEMBL3791294 | 0.64 | — | — | |
| SCHEMBL12523285 | 0.64 | — | — | |
| SCHEMBL7637637 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110872295-B | Method for synthesizing imidazo [1,2-a ] indole compound | 浙江工业大学 | 2021-07-27 | — | — | CN | claimed |
| CN-110872295-A | Method for synthesizing imidazo [1,2-a ] indole compound | 浙江工业大学 | 2020-03-10 | — | — | CN | claimed |
| CN-110872257-A | Method for synthesizing imidazole compound | 浙江工业大学 | 2020-03-10 | — | — | CN | claimed |
| US-6100373-A | Functionalized diene monomers and polymers containing functionalized dienes and methods for their preparation | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2000-08-08 | — | — | US | claimed |
| EP-0832059-A1 | METHOD FOR THE PREPARATION OF AN N-(2-BROMOALKYL)-AMIDE DERIVATIVE | DSM N.V. (NL) | 1998-04-01 | — | — | EP | claimed |
| WO-1997000237-A1 | PROCESS FOR THE PREPARATION OF AN N-(2-BROMOALKYL)-AMIDE DERIVATE_______________________________________________________________ | DSM N.V. (NL) | 1997-01-03 | — | — | WO | claimed |
| US-20250026721-A1 | COMPOUNDS AND METHODS FOR MODULATING RAS-PI3K | VIVIDION THERAPEUTICS, INC. | 2025-01-23 | — | — | US | disclosed |
| US-12162871-B2 | Inhibitors of VAP-1 | ACUCELA INC. (US) | 2024-12-10 | — | — | US | disclosed |
| US-20240067612-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. | 2024-02-29 | — | — | US | disclosed |
| US-20240067612-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. | 2024-02-29 | — | — | US | disclosed |
| WO-2024010782-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |
| US-11787791-B2 | Inhibitors of VAP-1 | ACUCELA INC. (US) | 2023-10-17 | — | — | US | disclosed |
| US-11787791-B2 | Inhibitors of VAP-1 | ACUCELA INC. (US) | 2023-10-17 | — | — | US | disclosed |
| EP-0523904-A1 | Process for preparing azetidin-2-one derivatives | Takasago International Corporation (JP) | 1993-01-20 | — | — | EP | disclosed |
| EP-0282492-A1 | ANTIMICROBIAL N-ACYL-2-AZETIDINONES | THE UPJOHN COMPANY (US) | 1988-09-21 | — | — | EP | disclosed |
| EP-0282492-A1 | ANTIMICROBIAL N-ACYL-2-AZETIDINONES | THE UPJOHN COMPANY (US) | 1988-09-21 | — | — | EP | disclosed |
| EP-0232017-A1 | Antimicrobial N-acyl-2-azetidinones | THE UPJOHN COMPANY (US) | 1987-08-12 | — | — | EP | disclosed |
| EP-0232017-A1 | Antimicrobial N-acyl-2-azetidinones | THE UPJOHN COMPANY (US) | 1987-08-12 | — | — | EP | disclosed |
| WO-1987004429-A1 | ANTIMICROBIAL N-ACYL-2-AZETIDINONES | THE UPJOHN COMPANY (US) | 1987-07-30 | — | — | WO | disclosed |
| WO-1987004429-A1 | ANTIMICROBIAL N-ACYL-2-AZETIDINONES | THE UPJOHN COMPANY (US) | 1987-07-30 | — | — | WO | disclosed |