Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 6/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.50 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | PRCP | P42785 | 4/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3213021 | 1.00 | HCRTR1 (0.50) | HCRTR1HCRTR2AADATGRIN2BPRCP | |
| SCHEMBL3209134 | 0.93 | HCRTR1 (0.59) | HCRTR1HCRTR2AADATGRIN2BPRCP | |
| SCHEMBL12075233 | 0.93 | HCRTR1 (0.59) | HCRTR1HCRTR2AADATGRIN2BPRCP | |
| SCHEMBL12509691 | 0.90 | AADAT (0.47) | HCRTR1HCRTR2AADATGRIN2BPRCP | |
| SCHEMBL13191114 | 0.89 | GRIN2B (0.48) | HCRTR1HCRTR2AADATGRIN2BPRCP | |
| SCHEMBL2193341 | 0.89 | AADAT (0.46) | HCRTR1HCRTR2AADATGRIN2BPRCP | |
| SCHEMBL1045345 | 0.89 | AADAT (0.46) | HCRTR1HCRTR2AADATGRIN2BPRCP | |
| SCHEMBL14948408 | 0.88 | AADAT (0.46) | HCRTR1HCRTR2AADATTMEM97SIGMAR1 | |
| SCHEMBL933934 | 0.88 | AADAT (0.46) | HCRTR1HCRTR2AADATGRIN2BPRCP | |
| SCHEMBL12509784 | 0.88 | TMEM97 (0.49) | HCRTR1HCRTR2AADATGRIN2BPRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100055071-A1 | Anti-Viral Compounds | SMITHKLINE BEECHAM CORPORATION | 2010-03-04 | — | — | US | disclosed |
| EP-2097405-A2 | ANTI-VIRAL COMPOUNDS | Smithkline Beecham Corporation (US) | 2009-09-09 | — | — | EP | disclosed |
| US-20080193411-A1 | Anti-viral Compounds | GENELABS TECHNOLOGIES, INC. | 2008-08-14 | — | — | US | disclosed |
| WO-2008070447-A2 | ANTI-VIRAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080193411-A1 | Anti-viral Compounds | ZC3HAV1, ZC3HAV1L, SARS1 | HCRTR1 2912/4885HCRTR2 3926/4885AADAT 2338/4885 |
| US-20100055071-A1 | Anti-Viral Compounds | ZC3HAV1, ZC3HAV1L, SARS1 | HCRTR1 2912/4885HCRTR2 3926/4885AADAT 2338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.