⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27362930 | 0.83 | — | — | |
| SCHEMBL12380275 | 0.78 | — | — | |
| SCHEMBL26755328 | 0.74 | — | — | |
| SCHEMBL1988780 | 0.74 | — | — | |
| SCHEMBL371255 | 0.74 | — | — | |
| SCHEMBL7032277 | 0.74 | — | — | |
| SCHEMBL12940068 | 0.73 | — | — | |
| SCHEMBL863193 | 0.73 | — | — | |
| SCHEMBL435435 | 0.73 | — | — | |
| SCHEMBL19275065 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11452735-B2 | Pharmaceutical combinations of organo-arsenoxide compounds and mTOR inhibitors | NEWSOUTH INNOVATIONS PTY LIMITED | 2022-09-27 | — | — | US | disclosed |
| US-20200323887-A1 | Pharmaceutical Combinations of Organo-Arsenoxide Compounds and mTOR Inhibitors | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2020-10-15 | — | — | US | disclosed |
| US-20180140620-A1 | Pharmaceutical Combinations of Organo-Arsenoxide Compounds and mTOR Inhibitors | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2018-05-24 | — | — | US | disclosed |
| EP-3307263-A1 | PHARMACEUTICAL COMBINATIONS OF ORGANO-ARSENOXIDE COMPOUNDS AND MTOR INHIBITORS | NewSouth Innovations Pty Limited (AU) | 2018-04-18 | — | — | EP | disclosed |
| US-9765101-B2 | Organo-arsenoxide compounds and use thereof | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2017-09-19 | — | — | US | disclosed |
| WO-2016201481-A1 | PHARMACEUTICAL COMBINATIONS OF ORGANO-ARSENOXIDE COMPOUNDS AND MTOR INHIBITORS | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2016-12-22 | — | — | WO | disclosed |
| EP-2069371-B1 | ORGANO-ARSENOXIDE COMPOUNDS AND USE THEREOF | NEWSOUTH INNOVATIONS PTY LTD (AU) | 2013-03-13 | — | — | EP | disclosed |
| US-20130041027-A1 | Organo-Arsenoxide Compounds and Use Thereof | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2013-02-14 | — | — | US | disclosed |
| US-8268883-B2 | Organo-arsenoxide compounds and use thereof | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2012-09-18 | — | — | US | disclosed |
| US-20100041749-A1 | Organo-Arsenoxide Compounds and Use Thereof | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2010-02-18 | — | — | US | disclosed |
| EP-2069371-A1 | ORGANO-ARSENOXIDE COMPOUNDS AND USE THEREOF | Newsouth Innovations Pty Limited (AU) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008052279-A1 | ORGANO-ARSENOXIDE COMPOUNDS AND USE THEREOF | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2008-05-08 | — | — | WO | disclosed |