SCHEMBL435435

SCHEMBL435435

NC(C=O)CS

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL863193 1.00
SCHEMBL12940068 1.00
SCHEMBL14963190 0.79
SCHEMBL13716272 0.75
SCHEMBL7837665 0.75
SCHEMBL3214461 0.73
SCHEMBL127505 0.72 SLC6A2 (0.31)
SCHEMBL18019736 0.71
SCHEMBL436289 0.69
SCHEMBL9678445 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167109-A1 Aminopiperidine Amides, Derivatives, Compositions, and Uses Related to CXCR4 Modulation UNIV EMORY (US) 2023-06-01 US claimed
WO-2021217143-A1 AMINOPIPERIDINE AMIDES, DERIVATIVES, COMPOSITIONS, AND USES RELATED TO CXCR4 MODULATION EMORY UNIVERSITY (US) 2021-10-28 WO claimed
CN-110372080-A The inorganic agent of combined removal heavy metals in industrial wastewater ion 重庆工程职业技术学院 2019-10-25 CN claimed
EP-1140942-B1 PRENYL TRANSFERASE INHIBITORS CONSEILS DE RECH SET D APPLIC (FR) 2004-03-10 EP claimed
US-4719231-A 3-[N-(mercaptoacyl)]amino-4-arylbutanoic acid derivatives and an analgesic agent comprising the same ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1988-01-12 US claimed
WO-2024013355-A1 HYDROGELS FOR CELL THERAPY ADOCIA (FR) 2024-01-18 WO disclosed
EP-4306550-A1 HYDROGELS FOR CELL THERAPY Adocia (FR) 2024-01-17 EP disclosed
US-11779602-B2 Methods of use for CAR T cells ENDOCYTE, INC. (US) 2023-10-10 US disclosed
US-11779602-B2 Methods of use for CAR T cells ENDOCYTE, INC. (US) 2023-10-10 US disclosed
US-11759480-B2 Compositions and methods for CAR T cell therapy ENDOCYTE, INC. (US) 2023-09-19 US disclosed
US-20230167109-A1 Aminopiperidine Amides, Derivatives, Compositions, and Uses Related to CXCR4 Modulation UNIV EMORY (US) 2023-06-01 US disclosed
US-11311625-B2 Peptide-based multiple-drug delivery vehicle ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) 2022-04-26 US disclosed
WO-2007022494-A2 MULTI-DRUG LIGAND CONJUGATES ENDOCYTE, INC. (US) 2007-02-22 WO disclosed
WO-2007022493-A2 LIGAND CONJUGATES OF VINCA ALKALOIDS, ANALOGS, AND DERIVATIVES ENDOCYTE, INC. (US) 2007-02-22 WO disclosed
EP-1140942-B1 PRENYL TRANSFERASE INHIBITORS CONSEILS DE RECH SET D APPLIC (FR) 2004-03-10 EP disclosed
CN-1021910-C LANKACIDIN DERIVATIVES AND PRODUCTION THEREOF TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-08-25 CN disclosed
EP-0382411-A2 Delivery of cytotoxic agents ELI LILLY AND COMPANY (US) 1990-08-16 EP disclosed
US-4719231-A 3-[N-(mercaptoacyl)]amino-4-arylbutanoic acid derivatives and an analgesic agent comprising the same ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1988-01-12 US disclosed
CN-86108176-A Lankacidin derivatives and process for producing the same 1987-10-21 CN disclosed
US-4212795-A TO FORM DISULFIDE BOND ARMOUR PHARMACEUTICAL COMPANY (US) 1980-07-15 US disclosed