Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3217581 | 0.78 | PDGFRB (0.38) | NPSR1HTTHPGDLMNAPRNP | |
| SCHEMBL23429990 | 0.78 | ALDH1A1 (0.36) | NPSR1HTTPDGFRBPDGFRAALDH1A1 | |
| SCHEMBL3222941 | 0.78 | PLAU (0.39) | NPSR1HTTHPGDLMNAPRNP | |
| SCHEMBL18571995 | 0.74 | PDGFRB (0.38) | HTTPDGFRBEGFRPDGFRADYRK1A | |
| SCHEMBL18571804 | 0.74 | PLAU (0.39) | HTTHPGDPDGFRBEGFRPDGFRA | |
| SCHEMBL16537787 | 0.74 | PDGFRB (0.48) | PDGFRBPDGFRA | |
| SCHEMBL24637975 | 0.73 | CYP1A2 (0.47) | NPSR1HPGDPDGFRBEGFRPDGFRA | |
| SCHEMBL3892773 | 0.72 | EGFR (0.43) | NPSR1HPGDPDGFRBEGFRPDGFRA | |
| SCHEMBL18318734 | 0.71 | PDGFRB (0.51) | NPSR1PRNPPDGFRBPDGFRAALDH1A1 | |
| SCHEMBL6288436 | 0.71 | DYRK1A (0.38) | NPSR1HTTPDGFRBEGFRPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101522030-B | Fungicides | SYNGENTA PARTICIPATIONS AG | 2012-09-05 | — | — | CN | disclosed |
| US-20100056570-A1 | FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-03-04 | — | — | US | disclosed |
| CN-101522030-A | Fungicides | SYNGENTA PARTICIPATIONS AG (CH) | 2009-09-02 | — | — | CN | disclosed |
| EP-2068632-A1 | FUNGICIDES | Syngeta Participations AG (CH) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008028624-A1 | FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056570-A1 | FUNGICIDES | CYP21A2, CYP51A1, CYP4X1 | NPSR1 3200/4885HTT 3521/4885HPGD 3810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.