Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.30 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3149404 | 0.93 | SLC2A1 (0.44) | CYP19A1SLC2A1KCNH2TGFBR1TGFBR2 | |
| SCHEMBL3224644 | 0.85 | SLC2A1 (0.40) | SLC2A1KCNH2 | |
| SCHEMBL4554011 | 0.82 | SLC2A1 (0.39) | SLC2A1KCNH2 | |
| SCHEMBL3218053 | 0.82 | CYP19A1 (0.39) | CYP19A1 | |
| SCHEMBL3223237 | 0.80 | SLC2A1 (0.42) | SLC2A1KCNH2 | |
| SCHEMBL3224839 | 0.78 | SLC2A1 (0.47) | SLC2A1KCNH2 | |
| SCHEMBL3146445 | 0.78 | SLC2A1 (0.47) | SLC2A1KCNH2 | |
| SCHEMBL3326906 | 0.78 | SLC2A1 (0.47) | SLC2A1KCNH2 | |
| Hydrochloric Acid SCHEMBL3149069 | 0.77 | SLC2A1 (0.46) | SLC2A1KCNH2 | |
| SCHEMBL3549685 | 0.77 | KCNH2 (0.54) | CYP19A1SLC2A1KCNH2TGFBR1TGFBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056502-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056502-A1 | COMPOUNDS | NRDC, NACA, NAA50 | CYP19A1 3056/4885SLC2A1 4172/4885KCNH2 3105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.