Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | XIAP | P98170 | 1/20 | 0.61 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.61 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.53 |
| ▸ | GRB2 | P62993 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | CPA1 | P15085 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CTSC | P53634 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylalanine Amide SCHEMBL3215074 | 1.00 | ALPI (0.61) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL18241823 | 0.98 | ALPI (0.59) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL11349868 | 0.91 | SLC7A5 (0.73) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL244302 | 0.91 | SLC7A5 (0.73) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL353251 | 0.91 | SLC7A5 (0.73) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL244303 | 0.91 | SLC7A5 (0.73) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL23002157 | 0.89 | SLC7A5 (0.70) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL7613303 | 0.89 | SLC7A5 (0.70) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL353593 | 0.89 | SLC7A5 (0.70) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL7613300 | 0.89 | SLC7A5 (0.70) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103826661-B | Novel binding agent-drug conjugates (ADCs) and uses thereof | 西雅图基因公司 | 2019-03-05 | — | — | CN | disclosed |
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2010-02-04 | — | — | US | disclosed |
| US-5780588-A | ANTICARCINOGENIC AGENT | ARIZONA BOARD OF REGENTS (US) | 1998-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | ACIN1, HAT1, CCNE1 | ALPI 436/4885PKM 1417/4885PTGS1 4396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.