Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.58 |
| ▸ | KCNJ6 | P48051 | 3/20 | 0.43 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.43 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3198446 | 0.85 | PPARG (0.67) | PPARGKCNJ6KCNJ5KCNJ3FAAH | |
| SCHEMBL4613947 | 0.82 | PPARG (0.54) | PPARGKCNJ6KCNJ5KCNJ3FAAH | |
| SCHEMBL27716301 | 0.81 | PPARG (0.58) | PPARGKCNJ6KCNJ5KCNJ3FAAH | |
| SCHEMBL3210877 | 0.81 | PPARG (0.59) | PPARGKCNJ6KCNJ5KCNJ3FAAH | |
| SCHEMBL3205336 | 0.80 | PPARG (0.57) | PPARGKCNJ6KCNJ5KCNJ3FAAH | |
| SCHEMBL3212661 | 0.79 | NPC1 (0.49) | PPARGPTGDR2GABRA2GABRB2CCR2 | |
| SCHEMBL3206852 | 0.79 | PPARG (0.67) | PPARGKCNJ6KCNJ5KCNJ3FAAH | |
| SCHEMBL3206869 | 0.79 | PPARG (0.67) | PPARGKCNJ6KCNJ5KCNJ3FAAH | |
| SCHEMBL3221727 | 0.77 | PPARG (0.54) | PPARGKCNJ6KCNJ5KCNJ3PTGDR2 | |
| SCHEMBL3198995 | 0.75 | PPARG (0.81) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041892-A1 | Therapeutic agent for diabetes | ABE HIDENORI | 2010-02-18 | — | — | US | disclosed |
| US-20090270631-A1 | Therapeutic agent for diabetes | ABE HIDENORI | 2009-10-29 | — | — | US | disclosed |
| US-20080009530-A1 | Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270631-A1 | Therapeutic agent for diabetes | FABP4, SLC5A1, SLC5A2 | PPARG 31/4885KCNJ6 3589/4885KCNJ5 3431/4885 |
| US-20080009530-A1 | Therapeutic Agent for Diabetes | FABP4, SLC5A1, SLC5A2 | PPARG 30/4885KCNJ6 3134/4885KCNJ5 2900/4885 |
| US-20100041892-A1 | Therapeutic agent for diabetes | FABP4, SLC5A1, SLC5A2 | PPARG 31/4885KCNJ6 3589/4885KCNJ5 3431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.