SCHEMBL321699

SCHEMBL321699

CCOC(=O)C(C)=Cc1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.74
KMT2A Q03164 6/20 0.74
MAPT P10636 7/20 0.58
LMNA P02545 5/20 0.58
NPSR1 Q6W5P4 3/20 0.58
S1PR4 O95977 1/20 0.58
S1PR1 P21453 1/20 0.58
MAPK1 P28482 1/20 0.58
AKR1C3 P42330 1/20 0.58
NR1H4 Q96RI1 1/20 0.55
CYP1A2 P05177 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
SMN1; SMN2 Q16637 3/20 0.53
ALDH1A1 P00352 6/20 0.51
KDM4E B2RXH2 3/20 0.51
HSP90AA1 P07900 1/20 0.51
HPGD P15428 1/20 0.51
POLB P06746 2/20 0.50
PLIN1 O60240 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL321698 1.00 MEN1 (0.74) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL10395471 0.87 MEN1 (0.66) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL10395470 0.87 MEN1 (0.66) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL1683262 0.86 MEN1 (0.56) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL22572668 0.86 KMT2A (0.56) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL3609468 0.86 MAPT (0.58) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL3609471 0.86 MAPT (0.58) MEN1KMT2AMAPTLMNANPSR1
Benzene SCHEMBL27988126 0.85 MEN1 (1.00) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL935186 0.85 MEN1 (1.00) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL5694705 0.85 MEN1 (0.54) MEN1KMT2AMAPTLMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240065944-A1 Biocompatible Enamel-Dentin Single-Component Adhesives IVOCLAR VIVADENT AG (LI) 2024-02-29 US claimed
EP-1700139-B1 INTRAOCULAR LENS MATERIALS SUITABLE FOR INSERTION THROUGH A SMALL BORE CARTRIDGE ABBOTT MEDICAL OPTICS INC (US) 2009-10-21 EP claimed
EP-0108886-A2 Silicone-containing hard contact lens materials having increased oxygen permeability CIBA-GEIGY AG (CH) 1984-05-23 EP claimed
JP-9174647-A None JP disclosed
EP-3962413-B1 A NEW ADVANCED FORMULATION FOR HYDROPHOBIC INTRAOCULAR LENSES AND THEIR PRODUCTION METHOD VSY BIYOTEKNOLOJI VE ILAC SANAYI ANONIM SIRKETI (TR) 2026-04-08 EP disclosed
CN-119431642-A Resin particle composition, detection kit, and method for producing resin particle composition 赛登化学株式会社 2025-02-14 CN disclosed
CN-109124826-B Ophthalmic lens 爱博诺德(北京)医疗科技股份有限公司 2025-01-10 CN disclosed
CN-115975105-B Soft intraocular lens material and soft intraocular lens 株式会社尼德克 2024-11-19 CN disclosed
CN-115298573-B High refractive index silicone insert materials for embedded contact lenses 爱尔康公司 2024-09-06 CN disclosed
US-11925686-B2 Materials for phototherapies of ophthalmic diseases EYEBRIGHT MEDICAL TECHNOLOGY (BEIJING) CO., LTD. (CN) 2024-03-12 US disclosed
CN-117618255-A Biocompatible enamel-dentin single component adhesive 义获嘉伟瓦登特公司 2024-03-01 CN disclosed
EP-0240138-B1 PREPARATION OF CINNAMIC ACIDS MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-09-18 EP disclosed
EP-0279474-B1 PROCESS FOR THE PREPARATION OF AN ESTER OF A 3-ARYL-SUBSTITUTED ACRYLIC ACID SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-09-11 EP disclosed
EP-0328145-A2 Plastics containing discrete particles with functional materials DOW CORNING CORPORATION (US) 1989-08-16 EP disclosed
US-4806683-A Preparation process of cinnamic acids MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1989-02-21 US disclosed
EP-0279474-A1 Process for the preparation of an ester of a 3-aryl-substituted acrylic acid SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-08-24 EP disclosed
EP-0240138-A1 Preparation of cinnamic acids MITSUI TOATSU CHEMICALS, Inc. (JP) 1987-10-07 EP disclosed
US-4620954-A Hydrogel from ultraviolet-initiated copolymerization CIBA VISION CARE CORP. (US) 1986-11-04 US disclosed
EP-0108886-A2 Silicone-containing hard contact lens materials having increased oxygen permeability CIBA-GEIGY AG (CH) 1984-05-23 EP disclosed
US-3955282-A Process of mounting orthodontic bracket to tooth MCNALL EARL G 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11925686-B2 Materials for phototherapies of ophthalmic diseases ALDH1A2, LCP1, PDE6C MEN1 1363/4885KMT2A 2153/4885MAPT 487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.