Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5138360 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1DNM1LMNATP53 | |
| Bromide SCHEMBL475827 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1DNM1LMNATP53 | |
| Bromide SCHEMBL489783 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1DNM1LMNATP53 | |
| Bromide SCHEMBL923748 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1DNM1LMNATP53 | |
| Bromide SCHEMBL139792 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1DNM1LMNATP53 | |
| Bromide SCHEMBL924077 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1DNM1LMNATP53 | |
| Bromide SCHEMBL3092841 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1DNM1LMNATP53 | |
| Bromide SCHEMBL923753 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1DNM1LMNATP53 | |
| Bromide SCHEMBL5088250 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1DNM1LMNATP53 | |
| SCHEMBL8383457 | 0.98 | OPRM1 (0.48) | OPRM1SPHK1DNM1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240002612-A1 | FIBER-REINFORCED PULTRUSION-MOLDED ARTICLE | TORAY INDUSTRIES, INC. (JP) | 2024-01-04 | — | — | US | disclosed |
| EP-4257624-A1 | FIBER-REINFORCED PULTRUSION-MOLDED ARTICLE | Toray Industries, Inc. (JP) | 2023-10-11 | — | — | EP | disclosed |
| CN-116507653-A | Drawn fiber-reinforced molded article | 东丽株式会社 | 2023-07-28 | — | — | CN | disclosed |
| WO-2022118827-A1 | FIBER-REINFORCED PULTRUSION-MOLDED ARTICLE | 東レ株式会社 | 2022-06-09 | — | — | WO | disclosed |
| US-10794809-B2 | Method for urine sample analysis, reagent for urine sample analysis, and reagent kit for urine sample analysis | SYSMEX CORPORATION (JP) | 2020-10-06 | — | — | US | disclosed |
| CN-107406607-B | Two-component epoxy resin composition for fiber-reinforced composite material, and fiber-reinforced composite material | 东丽株式会社 | 2020-07-10 | — | — | CN | disclosed |
| US-10464811-B2 | Method of forming a particulate porous metal oxide or metalloid oxide | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2019-11-05 | — | — | US | disclosed |
| EP-3112863-B1 | METHOD FOR DETECTING CASTS AND ERYTHROCYTES IN URINE SAMPLES | SYSMEX CORP (JP) | 2019-07-17 | — | — | EP | disclosed |
| EP-3112863-A1 | METHOD FOR URINE SAMPLE ANALYSIS, REAGENT FOR URINE SAMPLE ANALYSIS, AND REAGENT KIT FOR URINE SAMPLE ANALYSIS | Sysmex Corporation (JP) | 2017-01-04 | — | — | EP | disclosed |
| US-20160363521-A1 | METHOD FOR URINE SAMPLE ANALYSIS, REAGENT FOR URINE SAMPLE ANALYSIS, AND REAGENT KIT FOR URINE SAMPLE ANALYSIS | SYSMEX CORPORATION (JP) | 2016-12-15 | — | — | US | disclosed |
| US-20100254890-A1 | METHOD OF FORMING A PARTICULATE POROUS METAL OXIDE OR METALLOID OXIDE | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2010-10-07 | — | — | US | disclosed |