SCHEMBL3218833

SCHEMBL3218833

CC(NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)NC(=O)C(N)C(C)C)C(C)O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 6/20 0.49
▸ BACE1 P56817 3/20 0.48
▸ NPY5R Q15761 3/20 0.46
▸ NPY1R P25929 2/20 0.46
▸ NPY4R P50391 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3218913 1.00 IL23R (0.49) IL23RBACE1NPY5RNPY1RNPY4R
SCHEMBL30558305 0.87 NPY4R (0.51) BACE1NPY5RNPY1RNPY4R
SCHEMBL29815593 0.86 KISS1R (0.52) BACE1NPY5RNPY1RNPY4R
SCHEMBL29883741 0.86 IL23R (0.46) IL23RNPY5RNPY1RNPY4R
SCHEMBL31265328 0.86 NPY4R (0.49) NPY5RNPY1RNPY4R
SCHEMBL30302999 0.86 NPY4R (0.51) NPY5RNPY1RNPY4R
SCHEMBL30866942 0.85 NPY4R (0.55) BACE1NPY5RNPY1RNPY4R
SCHEMBL30537833 0.84 TFPI (0.61) IL23RNPY5RNPY1RNPY4R
SCHEMBL31410845 0.84 TFPI (0.56) IL23RNPY5RNPY1RNPY4R
SCHEMBL29397501 0.83 BACE1 (0.53) BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8962697-B2 Bioreponsive polymers INTERFACE BIOLOGICS INC. (CA) 2015-02-24 — — US disclosed
US-20100041771-A1 Bioreponsive Polymers INTERFACE BIOLOGICS, INC. 2010-02-18 — — US disclosed
EP-2040758-A2 BIORESPONSIVE POLYMERS Interface Biologics Inc. (CA) 2009-04-01 — — EP disclosed
WO-2008053362-A2 BIORESPONSIVE POLYMERS INTERFACE BIOLOGICS, INC. (CA) 2008-05-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041771-A1 Bioreponsive Polymers PEPD, PREP, DNPEP IL23R 3742/4885BACE1 383/4885NPY5R 2786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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