Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22807230 | 0.84 | KDM4E (0.39) | KDM4EALDH1A1KMT2AMEN1MAP3K5 | |
| SCHEMBL21602152 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1KMT2AMEN1MAP3K5 | |
| SCHEMBL243257 | 0.82 | MAPT (0.50) | KDM4EALDH1A1KMT2AMEN1MAP3K5 | |
| SCHEMBL21595222 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1KMT2AMEN1MAP3K5 | |
| SCHEMBL8170672 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1KMT2AMEN1MAP3K5 | |
| SCHEMBL4832474 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1KMT2AMEN1MAP3K5 | |
| SCHEMBL4832463 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1KMT2AMEN1MAP3K5 | |
| SCHEMBL5269164 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1KMT2AMEN1MAP3K5 | |
| Hydrochloric Acid SCHEMBL30101396 | 0.81 | MAPT (0.53) | KDM4EALDH1A1KMT2AMEN1MAP3K5 | |
| Hydrochloric Acid SCHEMBL27665004 | 0.81 | MAPT (0.53) | KDM4EALDH1A1KMT2AMEN1MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11267826-B2 | Penicillin-binding protein inhibitors | VenatoRx Pharmaceuticals, Inc. (US) | 2022-03-08 | — | — | US | disclosed |
| US-20200102331-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-04-02 | — | — | US | disclosed |
| US-20200102331-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-04-02 | — | — | US | disclosed |
| US-9123895-B2 | Photovoltaic cell with thiazole-containing polymer | MERCK PATENT GMBH (DE) | 2015-09-01 | — | — | US | disclosed |
| US-20140034129-A1 | Photovoltaic Cell With Thiazole-Containing Polymer | MERCK PATENT GMBH (DE) | 2014-02-06 | — | — | US | disclosed |
| US-8563678-B2 | Photovoltaic cell with thiazole-containing polymer | MERCK PATENT GMBH (DE) | 2013-10-22 | — | — | US | disclosed |
| US-8008424-B2 | for use as charge carriers; a cyclopentadithiazole copolymer | KONARKA TECHNOLOGIES, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| US-8008424-B2 | for use as charge carriers; a cyclopentadithiazole copolymer | KONARKA TECHNOLOGIES, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| WO-2010008775-A1 | AMINOPYRIDOPYRAZINONE DERIVATIVES FOR TREATING NEURODEGENERATIVE DISEASES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | disclosed |
| WO-2008067023-A2 | PHOTOVOLTAIC CELL WITH THIAZOLE-CONTAINING POLYMER | KONARKA TECHNOLOGIES, INC. (US) | 2008-06-05 | — | — | WO | disclosed |
| US-20080121281-A1 | Photovoltaic Cell With Thiazole-Containing Polymer | KONARKA TECHNOLOGIES, INC. (US) | 2008-05-29 | — | — | US | disclosed |
| US-20080121281-A1 | Photovoltaic Cell With Thiazole-Containing Polymer | KONARKA TECHNOLOGIES, INC. (US) | 2008-05-29 | — | — | US | disclosed |
| US-6048852-A | BACTERICIDES | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-04-11 | — | — | US | disclosed |
| EP-0900197-A1 | BETA-THIOPROPIONYL-AMINOACID DERIVATIVES AND THEIR USE AS BETA-LACTAMASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997030027-A1 | BETA-THIOPROPIONYL-AMINOACID DERIVATIVES AND THEIR USE AS BETA-LACTAMASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1997-08-21 | — | — | WO | disclosed |
| EP-0039595-A1 | Total synthesis of 1RS,4SR,5RS-4-(4,8-dimethyl-5-hydroxy-7-nonen-1-yl)-4-methyl-3,8-dioxabicyclo(3.2.1)octane-1-acetic acid and related compounds | ORTHO PHARMACEUTICAL CORPORATION (US) | 1981-11-11 | — | — | EP | disclosed |
| US-4282220-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11267826-B2 | Penicillin-binding protein inhibitors | PEPD, BPGM, EBPL | KDM4E 2087/4885ALDH1A1 2794/4885KMT2A 2536/4885 |
| US-20200102331-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | PEPD, BPGM, EBPL | KDM4E 2087/4885ALDH1A1 2794/4885KMT2A 2536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.