Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24776144 | 1.00 | GAA (0.37) | GAAALPLCA2AKR1B1NR3C2 | |
| SCHEMBL24776758 | 0.88 | NR3C2 (0.39) | GAACA2AKR1B1NR3C2NR3C1 | |
| SCHEMBL24776143 | 0.84 | GAA (0.37) | GAACA2AKR1B1LTA4HDAO | |
| SCHEMBL24776225 | 0.84 | GAA (0.37) | GAACA2AKR1B1LTA4HDAO | |
| SCHEMBL17363926 | 0.82 | AKR1B1 (0.41) | GAACA2AKR1B1NR3C2NR3C1 | |
| SCHEMBL17363798 | 0.82 | AKR1B1 (0.41) | GAACA2AKR1B1NR3C2NR3C1 | |
| SCHEMBL17363916 | 0.82 | AKR1B1 (0.41) | GAACA2AKR1B1NR3C2NR3C1 | |
| SCHEMBL3591700 | 0.81 | GAA (0.37) | GAACREBBPMAPT | |
| SCHEMBL3587070 | 0.81 | GAA (0.37) | GAACREBBPMAPT | |
| SCHEMBL13544000 | 0.81 | GAA (0.37) | GAACREBBPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022262736-A1 | BENZOXAZINONE DERIVATIVES | 正大天晴药业集团股份有限公司 | 2022-12-22 | — | — | WO | disclosed |
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | WYETH | 2010-02-11 | — | — | US | disclosed |
| WO-2008052075-A2 | BENZOXAZINE DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | HTR2C, HTR5A, NPY1R | GAA 3565/4885ALPL 2044/4885CA2 3005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.