Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3219672 | 1.00 | PPARG (0.73) | PPARGALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL3202767 | 0.95 | PPARG (0.75) | PPARGALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL3202780 | 0.95 | PPARG (0.75) | PPARGALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL3219436 | 0.95 | PPARG (0.74) | PPARGALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL3219427 | 0.95 | PPARG (0.74) | PPARGALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL3197106 | 0.94 | PPARG (0.73) | PPARGALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL3197119 | 0.94 | PPARG (0.73) | PPARGALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL3213551 | 0.93 | PPARG (0.74) | PPARGALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL4529693 | 0.93 | PPARG (0.74) | PPARGALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL3204487 | 0.90 | PPARG (0.71) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041892-A1 | Therapeutic agent for diabetes | ABE HIDENORI | 2010-02-18 | — | — | US | disclosed |
| US-20090270631-A1 | Therapeutic agent for diabetes | ABE HIDENORI | 2009-10-29 | — | — | US | disclosed |
| US-20080009530-A1 | Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270631-A1 | Therapeutic agent for diabetes | FABP4, SLC5A1, SLC5A2 | PPARG 31/4885ALDH1A1 212/4885LMNA 1909/4885 |
| US-20080009530-A1 | Therapeutic Agent for Diabetes | FABP4, SLC5A1, SLC5A2 | PPARG 30/4885ALDH1A1 118/4885LMNA 2486/4885 |
| US-20100041892-A1 | Therapeutic agent for diabetes | FABP4, SLC5A1, SLC5A2 | PPARG 31/4885ALDH1A1 212/4885LMNA 1909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.