Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.91 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | RXRA | P19793 | 2/20 | 0.66 |
| ▸ | RXRB | P28702 | 2/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | DHODH | Q02127 | 2/20 | 0.61 |
| ▸ | ERN1 | O75460 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.56 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.56 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.56 |
| ▸ | FEN1 | P39748 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14683877 | 0.98 | KMO (0.87) | KMOLMNAGAARXRARXRB | |
| SCHEMBL29577419 | 0.98 | KMO (0.87) | KMOLMNAGAARXRARXRB | |
| SCHEMBL30436085 | 0.98 | KMO (0.95) | KMOLMNAGAARXRARXRB | |
| SCHEMBL31752544 | 0.98 | KMO (0.95) | KMOLMNAGAARXRARXRB | |
| SCHEMBL250880 | 0.98 | KMO (0.95) | KMOLMNAGAARXRARXRB | |
| Biphenyl SCHEMBL9652651 | 0.95 | KMO (0.91) | KMOLMNAGAARXRARXRB | |
| SCHEMBL849169 | 0.95 | KMO (1.00) | KMOLMNAGAARXRARXRB | |
| Hydrochloric Acid SCHEMBL30713416 | 0.95 | KMO (0.91) | KMOLMNAGAARXRARXRB | |
| SCHEMBL28690696 | 0.95 | KMO (0.91) | KMOLMNAGAARXRARXRB | |
| SCHEMBL28702560 | 0.95 | KMO (0.91) | KMOLMNAGAARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683097-B2 | Topoisomerase inhibitors | Propharmacon Inc. (US) | 2010-03-23 | — | — | US | claimed |