⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24724749 | 0.75 | — | — | |
| SCHEMBL4953524 | 0.75 | — | — | |
| SCHEMBL3069579 | 0.73 | — | — | |
| SCHEMBL3291885 | 0.69 | — | — | |
| SCHEMBL38663476 | 0.68 | TSHR (0.46) | — | |
| SCHEMBL3293919 | 0.67 | — | — | |
| SCHEMBL241029 | 0.67 | — | — | |
| SCHEMBL5176036 | 0.67 | — | — | |
| SCHEMBL4099364 | 0.67 | — | — | |
| SCHEMBL3082231 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103613588-A | Preparation technique of dasatinib | ANHUI YOUCARE KAIYUE PHARMACEUTICAL CO LTD | 2014-03-05 | — | — | CN | claimed |
| CN-103917528-B | PYRIMIDINE PDE10 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-04-20 | — | — | CN | disclosed |
| CN-103917528-A | Pyrimidine PDE10 inhibitors | MERCK SHARP & DOHME | 2014-07-09 | — | — | CN | disclosed |
| CN-103613588-A | Preparation technique of dasatinib | ANHUI YOUCARE KAIYUE PHARMACEUTICAL CO LTD | 2014-03-05 | — | — | CN | disclosed |
| CN-101195672-B | Method for producing olefin-copolymerization catalyst and method for producing olefin-copolymers | SUMITOMO CHEMICAL CO | 2011-07-06 | — | — | CN | disclosed |
| US-20100144722-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS GATA MODULATORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-06-10 | — | — | US | disclosed |
| US-7732540-B2 | Process for producing olefin copolymerization catalyst and process for producing olefin copolymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| WO-2010028179-A1 | HETEROCYCLIC COMPOUNDS AS GATA MODULATORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-03-11 | — | — | WO | disclosed |
| US-20090018012-A1 | Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-01-15 | — | — | US | disclosed |
| CN-101195672-A | Method for producing olefin-copolymerization catalyst and method for producing olefin-copolymers | SUMITOMO CHEMICAL CO (JP) | 2008-06-11 | — | — | CN | disclosed |
| CN-101035780-A | Substituted nitrogen-containing six-membered amino-heterocycles as vanilloid-1 receptor antagonists for treating pain | MERCK SHARP & DOHME (GB) | 2007-09-12 | — | — | CN | disclosed |