SCHEMBL3221175

SCHEMBL3221175

COc1ccccc1C1(OC)CC(=O)c2ccccc2O1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44
ATM Q13315 1/20 0.41
CYP19A1 P11511 1/20 0.39
MIF P14174 1/20 0.39
SIGMAR1 Q99720 1/20 0.37
KMT2A Q03164 1/20 0.37
MAOB P27338 2/20 0.36
NPC1 O15118 1/20 0.36
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
AVPR1A P37288 1/20 0.36
HTR2C P28335 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2120395 0.81 ATM (0.44) L3MBTL1ATMCYP19A1SIGMAR1MAOB
SCHEMBL7154660 0.80 MAOB (0.47) L3MBTL1ATMCYP19A1KMT2AMAOB
SCHEMBL7118017 0.76 PPIB (0.43) L3MBTL1ATMCYP19A1MAOBNPC1
SCHEMBL15346163 0.74 ATM (0.48) L3MBTL1ATMSIGMAR1MAOBNPC1
SCHEMBL30576331 0.74 ATM (0.48) L3MBTL1ATMSIGMAR1MAOBNPC1
SCHEMBL28862097 0.71 CYP19A1 (0.40) L3MBTL1CYP19A1SIGMAR1KMT2ANPC1
SCHEMBL27282516 0.69 SMN1; SMN2 (0.48) L3MBTL1ATMSIGMAR1KMT2AMAOB
SCHEMBL28387593 0.69 ALDH1A1 (0.54) CYP19A1MAOBHTR2C
SCHEMBL30065841 0.69 ALDH1A1 (0.60) ATMSIGMAR1MAOBNPC1MAPT
SCHEMBL544297 0.69 ALDH1A1 (0.60) ATMSIGMAR1MAOBNPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1542871-A1 METHOD FOR MAKING PRINTING PLATE BY INKJET DEPOSITION ON POSITIVE-WORKING MEDIA Creo SRL (CA) 2005-06-22 EP claimed
WO-2004007200-A1 METHOD FOR MAKING PRINTING PLATE BY INKJET DEPOSITION ON POSITIVE-WORKING MEDIA CREO SRL (CA) 2004-01-22 WO claimed
US-20180132516-A1 POSITIVE ALLOSTERIC MODULATORS OF SWEET TASTE SENSORYGEN INC (US) 2018-05-17 US disclosed
US-20100048494-A1 Natural Products from Vinca RICE UNIVERSITY (US) 2010-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048494-A1 Natural Products from Vinca HIRA, RDX, SLC22A8 L3MBTL1 4275/4885ATM 4622/4885CYP19A1 227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.