⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL11734679 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL28244693 | 0.95 | — | — | |
| SCHEMBL479164 | 0.74 | — | — | |
| SCHEMBL31524001 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL5103092 | 0.74 | — | — | |
| Trimethylammonium SCHEMBL9872020 | 0.71 | — | — | |
| Trimethylammonium SCHEMBL11572782 | 0.71 | — | — | |
| SCHEMBL12158626 | 0.70 | — | — | |
| SCHEMBL13177242 | 0.70 | — | — | |
| SCHEMBL15642983 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111093707-A | Tubulysin homolog conjugates containing branched linkers | 杭州多禧生物科技有限公司 | 2020-05-01 | — | — | CN | claimed |
| US-20100036119-A1 | FLUORINATING REAGENTS AND THEIR PREPARATION | LANXESS DEUTSCHLAND GMBH (DE) | 2010-02-11 | — | — | US | claimed |
| US-20050085474-A1 | Fluorinating reagents and their preparation | LANXESS DEUTSCHLAND GMBH (DE) | 2005-04-21 | — | — | US | claimed |
| EP-1437342-A2 | Fluorinating reactants and process for their preparation | Bayer Chemicals AG (DE) | 2004-07-14 | — | — | EP | claimed |
| JP-57024361-A | — | — | None | — | — | JP | disclosed |
| CN-117776980-A | Preparation method of bis- (N-bis (dimethylamino) methylene) -chloride iminium salt | 江苏丰山生化科技有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-111635321-B | Fluorinating agent and synthesis method thereof | 山东国邦药业有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-111362826-B | Preparation method of doxycycline intermediate 11 alpha-chloromethylmethacycline | 山东国邦药业有限公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-109311910-B | Tacrolimus conjugates, compositions thereof, and uses thereof | 杜兰教育基金委员会 | 2022-02-01 | — | — | CN | disclosed |
| CN-113330000-A | 3-carbonylamino-5-cyclopentyl-1 FI-pyrrole compound having inhibitory activity against CDK2 | 辉瑞公司 | 2021-08-31 | — | — | CN | disclosed |
| CN-107567438-B | Riluzole prodrugs and uses thereof | 拜尔哈文制药股份有限公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-111836798-A | Prodrugs of ketamine, compositions and uses thereof | 凯瑞康宁生物工程（武汉）有限公司 | 2020-10-27 | — | — | CN | disclosed |
| WO-1998047359-A1 | RAPID AND LONG LASTING BIOCIDAL SYSTEM | RHODIA LIMITED (GB) | 1998-10-29 | — | — | WO | disclosed |
| US-5733936-A | ANALGESICS | GRUENENTHAL GMBH (DE) | 1998-03-31 | — | — | US | disclosed |
| EP-0753506-A1 | 6-Dimethylaminomethyl-1-phenyl-cyclo-hexane compounds as pharmaceutical agents | Grünenthal GmbH (DE) | 1997-01-15 | — | — | EP | disclosed |
| EP-0449989-A1 | 6,7 DIHYDROPYRROLO 3,4-c] PYRIDO 2,3-d] PYRIMIDINE DERIVATIVES | Sloan-Kettering Institute For Cancer Research (US) | 1991-10-09 | — | — | EP | disclosed |
| WO-1990007496-A1 | 6,7 DIHYDROPYRROLO[3,4-c] PYRIDO[2,3-d] PYRIMIDINE DERIVATIVES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-07-12 | — | — | WO | disclosed |
| US-4925939-A | 6,7-dihydropyrrol[3,4-c]pyrido[2,3-d]pyrimidine derivatives | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-05-15 | — | — | US | disclosed |
| US-4474699-A | Preparing 1-aminomethyl-6-substituted-4H-s-triazolo[4,3-a][1,4]benzodiazepines in improved procedures | THE UPJOHN COMPANY (US) | 1984-10-02 | — | — | US | disclosed |
| JP-S5724361-A | PREPARATION OF INDOLE DERIVATIVE | PAAMAKEMU ASIA:KK | 1982-02-08 | — | — | JP | disclosed |