⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6283476 | 0.73 | TSHR (0.65) | — | |
| SCHEMBL151375 | 0.73 | TSHR (0.65) | — | |
| SCHEMBL132872 | 0.73 | DPP4 (0.47) | — | |
| SCHEMBL28353 | 0.73 | — | — | |
| SCHEMBL7032625 | 0.71 | TSHR (0.93) | — | |
| Water SCHEMBL11889376 | 0.71 | TSHR (0.93) | — | |
| Fluoride SCHEMBL28951268 | 0.71 | TSHR (0.93) | — | |
| Hydrogen Sulfide SCHEMBL21379318 | 0.71 | TSHR (0.61) | — | |
| Bromide SCHEMBL21831069 | 0.71 | TSHR (0.61) | — | |
| Hydrochloric Acid SCHEMBL28478207 | 0.71 | TSHR (0.93) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4767443-A | Antifungal and antibacterial diazine derivatives compositions, intermediates, and method of use therefor | CIBA-GEIGY CORPORATION (US) | 1988-08-30 | — | — | US | claimed |
| US-4740601-A | Imidazole derivatives having antimicrobial activities | SS PHARMACEUTICAL CO., LTD. (JP) | 1988-04-26 | — | — | US | claimed |
| US-4690923-A | ANTITHROMBOTICS | KARL THOMAE GMBH (DE) | 1987-09-01 | — | — | US | claimed |
| US-4341551-A | HERBICIDES, FUNGICIDES, PLANT GROWTH REGULATORS | SCHERING AG (DE) | 1982-07-27 | — | — | US | claimed |
| US-4055568-A | YELLOW | BASF AKTIENGESELLSCHAFT (DT) | 1977-10-25 | — | — | US | claimed |
| EP-1616859-B1 | Substituted cyclohexyl carboxylic acid compounds | SEIKAGAKU KOGYO CO LTD (JP) | 2013-09-04 | — | — | EP | disclosed |
| EP-1619189-B1 | N-(3-acyl-2-hydroxyalkyl) cycloalkyl amide derivatives | SEIKAGAKU KOGYO CO LTD (JP) | 2013-09-04 | — | — | EP | disclosed |
| WO-2010014054-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-02-04 | — | — | WO | disclosed |
| WO-2009076345-A1 | METHODS AND COMPOSITIONS FOR PRODUCING DIFLUOROMETHYLENE-AND TRIFLUOROMETHYL-CONTAINING COMPOUNDS | IM & T RESEARCH, INC. (US) | 2009-06-18 | — | — | WO | disclosed |
| US-7199139-B2 | Medicinal compositions containing diuretic and insulin resistance-improving agent | SANKYO COMPANY, LIMITED (JP) | 2007-04-03 | — | — | US | disclosed |
| EP-1354602-B1 | MEDICINAL COMPOSITIONS CONTAINING DIURETIC AND INSULIN RESISTANCE-IMPROVING AGENT | SANKYO CO (JP) | 2006-10-04 | — | — | EP | disclosed |
| EP-1695716-A2 | Medicinal compositions containing diuretics and insulin sensitizers | Sankyo Company, Limited (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-4478833-A | ANTICOAGULANTS | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-10-23 | — | — | US | disclosed |
| EP-0023559-B1 | 2-(PERHYDRO-1,4-DIAZINO)-PYRIMIDO(5,4-D)PYRIMIDINES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1984-09-19 | — | — | EP | disclosed |
| US-4341551-A | HERBICIDES, FUNGICIDES, PLANT GROWTH REGULATORS | SCHERING AG (DE) | 1982-07-27 | — | — | US | disclosed |
| EP-0055444-A2 | Trisubstituted pyrimido(5,4-d)pyrimidines, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1982-07-07 | — | — | EP | disclosed |
| EP-0034743-A1 | Benzoxazoles, their preparation and their use as medicines | Dr. Karl Thomae GmbH (DE) | 1981-09-02 | — | — | EP | disclosed |
| EP-0023559-A1 | 2-(Perhydro-1,4-diazino)-pyrimido(5,4-d)pyrimidines, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1981-02-11 | — | — | EP | disclosed |
| US-4128412-A | Herbicidal composition and method using N-(2-ethylsulfonyl-1,3,4-thiadiazol-5-yl)-N-methyl-N'-methyl urea | BAYER AKTIENGESELLSCHAFT (DE) | 1978-12-05 | — | — | US | disclosed |
| US-4049670-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-20 | — | — | US | disclosed |