SCHEMBL6283476

SCHEMBL6283476

ClC(c1ccccc1)C(Cl)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.65
DPP4 P27487 2/20 0.47
F2 P00734 1/20 0.47
HTR2A P28223 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
CYP2D6 P10635 1/20 0.41
SRC P12931 1/20 0.41
SLC6A2 P23975 2/20 0.40
SLC6A4 P31645 2/20 0.40
SLC6A3 Q01959 2/20 0.40
CFTR P13569 1/20 0.40
GOPC Q9HD26 1/20 0.40
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7701251 0.87 TSHR (0.58) TSHRDPP4F2HTR2ATAAR1
SCHEMBL10939089 0.84 TSHR (0.55) TSHRDPP4F2HTR2ATAAR1
SCHEMBL306112 0.82 TSHR (0.52) TSHRDPP4F2TAAR1CYP2D6
SCHEMBL11814126 0.82 TSHR (0.52) TSHRDPP4F2HTR2ATAAR1
SCHEMBL498588 0.82 TSHR (0.52) TSHRDPP4F2TAAR1CYP2D6
SCHEMBL893216 0.82 TSHR (0.52) TSHRDPP4F2TAAR1CYP2D6
SCHEMBL304645 0.82 TSHR (0.52) TSHRDPP4F2TAAR1CYP2D6
SCHEMBL10936760 0.80 DPP4 (0.65) TSHRDPP4F2HTR2ATAAR1
SCHEMBL9750479 0.80 TSHR (0.50) TSHRDPP4F2TAAR1CYP2D6
SCHEMBL9661636 0.80 ADRA2C (0.50) TSHRHTR2ACYP2D6SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6967229-B2 Carbon-carbon initiators for use in golf balls ACUSHNET COMPANY (US) 2005-11-22 US claimed
US-20050009992-A1 Carbon-carbon initiators for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US claimed
US-4024092-A Polymer compositions containing stilbene halide additives FOSTER GRANT CO., INC. (US) 1977-05-17 US claimed
EP-4479479-B1 SILPHENYLENE POLYMERS WACKER CHEMIE AG (DE) 2025-08-13 EP disclosed
US-20250215260-A1 SILPHENYLENE POLYMERS WACKER CHEMIE AG (DE) 2025-07-03 US disclosed
CN-119256051-A Silicon phenylene Polymer 瓦克化学股份公司 2025-01-03 CN disclosed
EP-4479479-A1 SILPHENYLENE POLYMERS Wacker Chemie AG (DE) 2024-12-25 EP disclosed
WO-2023222203-A1 SILPHENYLENE POLYMERS WACKER CHEMIE AG (DE) 2023-11-23 WO disclosed
US-9056227-B2 Golf ball comprising a core having a shallow hardness gradient ACUSHNET COMPANY (US) 2015-06-16 US disclosed
US-8968117-B2 Dual-core comprising zero gradient center and positive gradient outer core layer ACUSHNET COMPANY (US) 2015-03-03 US disclosed
US-20130109506-A1 GOLF BALL COMPRISING A CORE HAVING A SHALLOW HARDNESS GRADIENT ACUSHNET COMPANY (US) 2013-05-02 US disclosed
EP-0092454-B1 HALOGENATED AROMATIC ISOCYANATES OR THEIR MIXTURES HAVING A DIPHENYL-METHANE STRUCTURE ELF ATOCHEM S.A. (FR) 1985-11-27 EP disclosed
EP-0070218-B1 HALOGENATED AROMATIC COMPOUNDS SUITABLE AS FIRE RETARDERS ELF ATOCHEM S.A. (FR) 1985-06-19 EP disclosed
EP-0144015-A1 Self-extinguishing compositions based on ethylene vinylacetate copolymers suitable for the preparation of foamed materials MONTEDIPE S.p.A. (IT) 1985-06-12 EP disclosed
EP-0092454-A1 Halogenated aromatic isocyanates or their mixtures having a diphenyl-methane structure ELF ATOCHEM S.A. (FR) 1983-10-26 EP disclosed
EP-0088650-A1 Application of chlorinated benzyl toluene and benzyl xylene to lubrication ELF ATOCHEM S.A. (FR) 1983-09-14 EP disclosed
EP-0088667-A1 Halogenated aromatic diamines, process for their preparation and their use in the preparation of polyurethanes ELF ATOCHEM S.A. (FR) 1983-09-14 EP disclosed
EP-0070218-A1 Halogenated aromatic compounds suitable as fire retarders ELF ATOCHEM S.A. (FR) 1983-01-19 EP disclosed
US-4024092-A Polymer compositions containing stilbene halide additives FOSTER GRANT CO., INC. (US) 1977-05-17 US disclosed
US-4011375-A POLYOLEFINS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1977-03-08 US disclosed