⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7585956 | 0.80 | ALDH1A1 (0.32) | — | |
| SCHEMBL2698143 | 0.73 | — | — | |
| SCHEMBL8036355 | 0.67 | — | — | |
| SCHEMBL1568122 | 0.66 | ALDH1A1 (0.35) | — | |
| SCHEMBL127066 | 0.63 | — | — | |
| SCHEMBL10849333 | 0.63 | — | — | |
| SCHEMBL4463520 | 0.62 | — | — | |
| SCHEMBL12816765 | 0.62 | — | — | |
| SCHEMBL2779576 | 0.62 | ALDH1A1 (0.48) | — | |
| SCHEMBL7474103 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100279936-A1 | SUBSTITUTED ACETYLENIC COMPOUNDS USEFUL FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2010-11-04 | — | — | US | claimed |
| EP-2061449-A1 | SUBSTITUTED ACETYLENIC COMPOUNDS USEFUL FOR THE TREATMENT OF DISEASES | Leo Pharma A/S (DK) | 2009-05-27 | — | — | EP | claimed |
| WO-2008019690-A1 | SUBSTITUTED ACETYLENIC COMPOUNDS USEFUL FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2008-02-21 | — | — | WO | claimed |
| EP-0447196-A1 | Boronic acid dyes | Hewlett-Packard Company (US) | 1991-09-18 | — | — | EP | claimed |
| EP-3394121-B1 | PROCESS FOR THE PREPARATION OF (CO) POLYMERS OF CONJUGATED DIENES IN THE PRESENCE OF A CATALYTIC SYSTEM COMPRISING A VANADIUM BIS-IMINE COMPLEX | VERSALIS SPA (IT) | 2023-06-07 | — | — | EP | disclosed |
| EP-3066140-B1 | STEREOREGULAR DIBLOCK POLYBUTADIENES HAVING A 1,4-CIS/SYNDIOTACTIC 1,2 STRUCTURE FROM STEREOSPECIFIC POLYMERIZATION | VERSALIS SPA (IT) | 2021-12-29 | — | — | EP | disclosed |
| CN-108137744-B | Process for preparing (co) polymers of conjugated dienes in the presence of a catalytic system comprising a vanadium bis-imine complex | 维尔萨利斯股份公司 | 2020-08-14 | — | — | CN | disclosed |
| EP-2742080-B1 | PROCESS FOR THE PREPARATION OF POLYMERS CONTAINING BENZOHETERO [1, 3]DIAZOLE UNITS | ENI SPA (IT) | 2020-06-17 | — | — | EP | disclosed |
| CN-107406460-B | Bis-thienobenzothienothiophene compounds and process for preparation thereof | 艾尼股份公司 | 2020-05-12 | — | — | CN | disclosed |
| US-10611862-B2 | Process for the preparation of (co)polymers of conjugated dienes in the presence of a catalytic system comprising a vanadium bis-imine complex | VERSALIS S.P.A. (IT) | 2020-04-07 | — | — | US | disclosed |
| US-10189987-B2 | Pneumatic tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2019-01-29 | — | — | US | disclosed |
| EP-3230291-B1 | BIS-THIENOBENZOTHIENOTHIOPHENE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | ENI SPA (IT) | 2019-01-23 | — | — | EP | disclosed |
| EP-0949322-B1 | A process for making overbased calcium sulfonate detergents | LUBRIZOL CORP (US) | 2004-03-10 | — | — | EP | disclosed |
| US-6383636-B2 | MOLDING MATERIALS; IMPACT STRENGTH, HEAT RESISTANCE, SOLVENT RESISTANCE | DIRECTOR-GENERAL OF NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, MINISTRY OF ECONOMY, TRADE AND INDUSTRY (JP) | 2002-05-07 | — | — | US | disclosed |
| US-20020007020-A1 | (2,5-disubstituted-1,4-phenylene oxide) block or graft copolymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-01-17 | — | — | US | disclosed |
| CN-1321693-A | [2,5-disubstd.-1,4-phenylene oxide) block or graft copolymer | NAT INTEGRATED INST OF IND TEC (JP) | 2001-11-14 | — | — | CN | disclosed |
| US-6268318-B1 | MIXING SULFONIC ACID, ALCOHOL AND CALCIUM COMPOUND | THE LUBRIZOL CORPORATION | 2001-07-31 | — | — | US | disclosed |
| US-6015778-A | Process for making overbased calcium sulfonate detergents using calcium oxide and a less than stoichiometric amount of water | THE LUBRIZOL CORPORATION (US) | 2000-01-18 | — | — | US | disclosed |
| EP-0949322-A2 | A process for making overbased calcium sulfonate detergents | THE LUBRIZOL CORPORATION (US) | 1999-10-13 | — | — | EP | disclosed |
| US-4708809-A | CONTROL PISTON RING STICKING AND PROMOTE GENERAL ENGINE CLEANLINESS | THE LUBRIZOL CORPORATION (US) | 1987-11-24 | — | — | US | disclosed |