Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CXCR6 | O00574 | 4/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13490329 | 0.93 | GRM5 (0.52) | GRM5LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL3213873 | 0.93 | GRM5 (0.52) | GRM5LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL3213604 | 0.92 | MEN1 (0.51) | GRM5MEN1KMT2AGAAMAPT | |
| SCHEMBL13490307 | 0.90 | NPC1 (0.51) | GRM5LMNAMEN1KMT2APOLB | |
| SCHEMBL13490421 | 0.89 | MEN1 (0.48) | GRM5LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL13490319 | 0.89 | MEN1 (0.48) | GRM5LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL3217312 | 0.89 | MEN1 (0.48) | GRM5LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL13490309 | 0.88 | MEN1 (0.47) | GRM5LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL13490741 | 0.88 | MEN1 (0.54) | GRM5LMNAMEN1KMT2APOLB | |
| SCHEMBL13490618 | 0.88 | MEN1 (0.54) | GRM5LMNAMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | ACIN1, HAT1, CCNE1 | GRM5 4172/4885LMNA 926/4885L3MBTL1 717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.