Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.86 |
| ▸ | DHODH | Q02127 | 3/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | CASP1 | P29466 | 1/20 | 0.66 |
| ▸ | CASP7 | P55210 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3228525 | 0.92 | TP53 (1.00) | TP53DHODHKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL5151890 | 0.86 | DHODH (0.69) | TP53DHODHKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL4249057 | 0.84 | KDM4E (0.68) | TP53DHODHKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL2281113 | 0.80 | MAPT (0.64) | TP53DHODHKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL1897298 | 0.79 | STAT3 (0.76) | TP53DHODHKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL29536364 | 0.79 | DHODH (1.00) | TP53DHODHKDM4ESMN1; SMN2LMNA | |
| SCHEMBL2467110 | 0.79 | DHODH (1.00) | TP53DHODHKDM4ESMN1; SMN2LMNA | |
| Cinchophen SCHEMBL25519 | 0.79 | KDM4E (1.00) | TP53DHODHKDM4ESMN1; SMN2ALDH1A1 | |
| Cinchophen SCHEMBL7588217 | 0.79 | KDM4E (1.00) | TP53DHODHKDM4ESMN1; SMN2ALDH1A1 | |
| Cinchophen SCHEMBL29376617 | 0.79 | KDM4E (1.00) | TP53DHODHKDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010020672-A1 | NOVEL PHENYL-QUINOLINE-CARBOXYLIC ACID PYRIDINE DERIVATIVES USEFUL AS MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS | NEUROSEARCH A/S (DK) | 2010-02-25 | — | — | WO | claimed |
| CN-112920115-A | Quinoline-4-formamide skeleton derivative and application thereof | 四川大学 | 2021-06-08 | — | — | CN | disclosed |
| WO-2010020672-A1 | NOVEL PHENYL-QUINOLINE-CARBOXYLIC ACID PYRIDINE DERIVATIVES USEFUL AS MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS | NEUROSEARCH A/S (DK) | 2010-02-25 | — | — | WO | disclosed |
| US-20070060573-A1 | Acyltryptophanols | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | FSHR, NPY1R, NPY2R | TP53 4286/4885DHODH 3439/4885KDM4E 2399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.