SCHEMBL3223559

SCHEMBL3223559

Cc1nc2ncnn2c(C2CCCCC2)c1-c1c(F)cc(OCCCN(C)C)cc1F

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 18/20 0.38
EGLN2 Q96KS0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4488290 0.90 PDE2A (0.35) PDE2AEGLN2
SCHEMBL4494001 0.90 PDE2A (0.35) PDE2AEGLN2
SCHEMBL4494835 0.90 PDE2A (0.35) PDE2AEGLN2
SCHEMBL4486210 0.87 PDE2A (0.35) PDE2AEGLN2
SCHEMBL4489091 0.85 EGLN2 (0.39) PDE2AEGLN2
SCHEMBL976565 0.82 PDE2A (0.43) PDE2A
SCHEMBL3217156 0.82 PDE2A (0.38) PDE2A
SCHEMBL4493516 0.81 PDE2A (0.37) PDE2A
SCHEMBL4486630 0.80 PDE2A (0.37) PDE2A
SCHEMBL3227894 0.80 PDE2A (0.39) PDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100056371-A1 Use of Azolopyrimidines for Controlling Phytopathogenic Harmful Fungi BASF SE (DE) 2010-03-04 US disclosed
EP-2117312-A1 USE OF AZOLOPYRIMIDINES FOR FIGHTING PLANT PATHOGENIC FUNGI BASF SE (DE) 2009-11-18 EP disclosed
WO-2008084027-A1 USE OF AZOLOPYRIMIDINES FOR FIGHTING PLANT PATHOGENIC FUNGI BASF SE (DE) 2008-07-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100056371-A1 Use of Azolopyrimidines for Controlling Phytopathogenic Harmful Fungi DPM1, TYMP, G6PD PDE2A 1728/4885EGLN2 2270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.