SCHEMBL3224166

SCHEMBL3224166

C=CC(=O)N(C)CC(C)C

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
CA1 P00915 2/20 0.37
CA12 O43570 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
ALDH1A1 P00352 2/20 0.32
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA4 P43681 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PSMB5 P28074 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL990635 0.84 TSHR (0.33) TSHRALDH1A1CHRNB2CHRNB4CHRNA3
SCHEMBL410346 0.83 TSHR (0.36) TSHRCA1CA12CA2CA9
SCHEMBL4812030 0.82 ALDH1A1 (0.32) TSHRALDH1A1PSMB5
Hydrochloric Acid SCHEMBL28669748 0.81 TSHR (0.31) TSHR
SCHEMBL14542176 0.80 ALDH1A1 (0.31) TSHRALDH1A1
SCHEMBL3888299 0.79 TSHR (0.40) TSHRCA1CA12CA2CA9
SCHEMBL372826 0.79 CA12 (0.48) TSHRCA1CA12CA2CA9
SCHEMBL94257 0.78
Lactic Acid SCHEMBL602566 0.78 TP53 (0.41)
SCHEMBL12254047 0.77 TYMP (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5252218-A Process for separating solid particulates from a nonaqueous suspension CARGILL, INCORPORATED (US) 1993-10-12 US claimed
EP-0085370-B1 NITROCELLULOSE FREE NAIL LACQUER COMPOSITIONS Wickhen Products, Inc. (US) 1987-09-16 EP claimed
US-11976075-B2 Inhibitors of the MYST family of lysine acetyl transferases Isosterix, Inc. 2024-05-07 US disclosed
US-20230303580-A1 INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES Isosterix, Inc. 2023-09-28 US disclosed
EP-3778039-B1 DIGITAL PRINTING INKS SUN CHEMICAL CORP (US) 2022-04-06 EP disclosed
US-11021620-B2 Digital printing inks SUN CHEMICAL CORPORATION (US) 2021-06-01 US disclosed
EP-3778039-A1 DIGITAL PRINTING INKS Sun Chemical Corporation (US) 2021-02-17 EP disclosed
EP-3110893-B1 DIGITAL PRINTING INKS SUN CHEMICAL CORP (US) 2020-12-23 EP disclosed
US-9957417-B2 Fast cure aspartate polysiloxane hybrid coating COVESTRO LLC (US) 2018-05-01 US disclosed
US-9676785-B2 HCV protease inhibitors and uses thereof CELGENE CAR LLC (BM) 2017-06-13 US disclosed
US-9561228-B2 ERK inhibitors and uses thereof CELGENE AVILOMICS RESEARCH, INC. (US) 2017-02-07 US disclosed
WO-1994012586-A1 POLYSILOXANE COATING AMERON, INC. (US) 1994-06-09 WO disclosed
US-5275645-A Protective coatings of polysiloxanes from basic solutions with amines and organometallic catalysts AMERON, INC. (US) 1994-01-04 US disclosed
EP-0563316-A1 POLYOXAZOLIDONES. FULLER H B LICENSING FINANC (US) 1993-10-06 EP disclosed
US-5138016-A Using zinc halide catalyst H. B. FULLER COMPANY (US) 1992-08-11 US disclosed
WO-1992011304-A1 NOVEL CATALYST FOR PRODUCTION OF OXAZOLIDINE COMPOUNDS H.B. FULLER LICENSING & FINANCING INC. (US) 1992-07-09 WO disclosed
US-4762703-A COPOLYMERS OF DIACETONEACRYLAMIDE AND (METH)ACRYLIC ACID ESTERS DOW CORNING CORP. (US) 1988-08-09 US disclosed
US-4747419-A LOW VISCOSITY FILM FORMER CONTAINING PIGMENT, HYDROPHOBIC/ HYDROPHICK COPOLYMER AND THINNER CHESEBROUGH-POND'S, INC. (US) 1988-05-31 US disclosed
EP-0085370-B1 NITROCELLULOSE FREE NAIL LACQUER COMPOSITIONS Wickhen Products, Inc. (US) 1987-09-16 EP disclosed
EP-0085370-A2 Nitrocellulose free nail lacquer compositions Wickhen Products, Inc. (US) 1983-08-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303580-A1 INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES KAT6A, KAT6B, KAT2A TSHR 4145/4885CA1 3845/4885CA12 4272/4885
US-11976075-B2 Inhibitors of the MYST family of lysine acetyl transferases KAT6A, KAT6B, KAT2A TSHR 4145/4885CA1 3845/4885CA12 4272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.