SCHEMBL3224355

SCHEMBL3224355

O=C1O[C@H](C2CCCCC2)C(=O)O[C@H]1C1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.35
ALDH1A1 P00352 1/20 0.35
KMT2A Q03164 1/20 0.31
DAO P14920 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13741942 1.00 MAPT (0.35) MAPTALDH1A1KMT2ADAO
SCHEMBL3217672 1.00 MAPT (0.35) MAPTALDH1A1KMT2ADAO
SCHEMBL13359366 1.00 MAPT (0.35) MAPTALDH1A1KMT2ADAO
SCHEMBL13324833 1.00 MAPT (0.35) MAPTALDH1A1KMT2ADAO
SCHEMBL3201514 0.89 KMT2A (0.34) MAPTKMT2A
SCHEMBL13742410 0.77 CHRM2 (0.32) MAPTALDH1A1KMT2A
SCHEMBL13742229 0.74
SCHEMBL11573115 0.70 ALDH1A1 (0.37) ALDH1A1
SCHEMBL29042446 0.70 ALDH1A1 (0.37) ALDH1A1
SCHEMBL31059342 0.70 MAPT (0.33) MAPTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7709596-B2 Cyclic alkyl substituted glycolides and polylactides therefrom BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2010-05-04 US disclosed
US-20100041902-A1 Cyclic alkyl substituted glycolides and polylactides therefrom BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2010-02-18 US disclosed
US-7579429-B2 Cyclic alkyl substituted glycolides and polylactides therefrom BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2009-08-25 US disclosed
US-20070142461-A1 Cyclic alkyl substituted glycolides and polylactides therefrom BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041902-A1 Cyclic alkyl substituted glycolides and polylactides therefrom UGCG, DDOST, MAGT1 MAPT 1179/4885ALDH1A1 4084/4885KMT2A 3428/4885
US-20070142461-A1 Cyclic alkyl substituted glycolides and polylactides therefrom UGCG, DDOST, MAGT1 MAPT 1179/4885ALDH1A1 4084/4885KMT2A 3428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.