SCHEMBL3224698

SCHEMBL3224698

Cc1cc(N(C)C)ccc1C1(c2ccc(N(C)C)cc2)OC(=O)c2cc(N(C)C)ccc21

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.82
ALDH1A1 P00352 4/20 0.82
CYP3A4 P08684 3/20 0.82
HSD17B10 Q99714 2/20 0.82
HIF1A Q16665 2/20 0.82
HPGD P15428 2/20 0.82
MEN1 O00255 4/20 0.66
KMT2A Q03164 4/20 0.66
LMNA P02545 5/20 0.46
MAPT P10636 5/20 0.46
POLB P06746 3/20 0.46
NPSR1 Q6W5P4 3/20 0.46
GPR55 Q9Y2T6 2/20 0.46
ALOX12 P18054 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CFTR P13569 1/20 0.39
GOPC Q9HD26 1/20 0.39
TP53 P04637 2/20 0.38
ALOX15 P16050 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4907834 0.92 TDP1 (0.69) TDP1ALDH1A1CYP3A4HSD17B10HIF1A
SCHEMBL29384978 0.92 ALDH1A1 (0.69) TDP1ALDH1A1CYP3A4HSD17B10HIF1A
SCHEMBL9319300 0.92 ALDH1A1 (0.69) TDP1ALDH1A1CYP3A4HSD17B10HIF1A
SCHEMBL28008 0.92 ALDH1A1 (0.69) TDP1ALDH1A1CYP3A4HSD17B10HIF1A
SCHEMBL8930953 0.90 ALDH1A1 (0.67) TDP1ALDH1A1CYP3A4HSD17B10HIF1A
SCHEMBL9319588 0.90 ALDH1A1 (0.67) TDP1ALDH1A1CYP3A4HSD17B10HIF1A
SCHEMBL18143522 0.90 ALDH1A1 (1.00) TDP1ALDH1A1CYP3A4HSD17B10HIF1A
SCHEMBL27188 0.90 ALDH1A1 (1.00) TDP1ALDH1A1CYP3A4HSD17B10HIF1A
SCHEMBL4851834 0.89 ALDH1A1 (0.65) TDP1ALDH1A1CYP3A4HSD17B10HIF1A
SCHEMBL9319978 0.89 TDP1 (0.68) TDP1ALDH1A1CYP3A4HSD17B10HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5238151-A None JP disclosed
US-9834022-B2 Thermal recording material MITSUBISHI PAPER MILLS LIMITED (JP) 2017-12-05 US disclosed
EP-3031611-B1 THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LTD (JP) 2017-09-27 EP disclosed
US-20160332469-A1 THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LIMITED (JP) 2016-11-17 US disclosed
EP-3031611-A1 THERMAL RECORDING MATERIAL Mitsubishi Paper Mills Limited (JP) 2016-06-15 EP disclosed
US-8288313-B2 Thermal recording material MITSUBISHI PAPER MILLS LIMITED (JP) 2012-10-16 US disclosed
US-20100069240-A1 THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LIMITED (JP) 2010-03-18 US disclosed
US-6960553-B2 Heat-sensitive recording material MITSUBISHI PAPER MILLS LTD. (JP) 2005-11-01 US disclosed
US-20030186810-A1 Heat-sensitive recording material MITSUBISHI PAPER MILLS LTD. 2003-10-02 US disclosed
EP-0885745-B1 Thermosensitive recording sheet set for preservation temperature control and method of using the sheet set OJI PAPER CO (JP) 2001-09-19 EP disclosed
US-5994262-A MULTILAYER; RECORDING SHEET CONTAINING ZINC SALT OF A SALICYLIC ACID; ADHESIVE LAYER CONTAINING A LEUCO DYE AND AN ESTER; TEMPERATURE CONTROL OJI PAPER CO., LTD. (JP) 1999-11-30 US disclosed
EP-0885745-A1 Thermosensitive recording sheet set for preservation temperature control and method of using the sheet set Oji Paper Co., Ltd. (JP) 1998-12-23 EP disclosed
EP-0349194-B1 Heat-sensitive record material KANZAKI PAPER MFG CO LTD (JP) 1994-01-05 EP disclosed
JP-H05238151-A THERMOSENSITIVE RECORDING MEDIUM OJI PAPER CO LTD 1993-09-17 JP disclosed
US-4985393-A Bis/hydroxyphenylthio/ Compounds KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1991-01-15 US disclosed
US-4977132-A CONTAINING FLUORAN DERIVATIVE, PHTHALIDE DERIVATIVE, PHENOLIC COMPOUND; STORAGE STABILITY KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-12-11 US disclosed
EP-0349194-A2 Heat-sensitive record material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-01-03 EP disclosed