Difenoconazole

Difenoconazole

SCHEMBL3224770

C[C@@H]1CO[C@](Cn2cncn2)(c2ccc(Oc3ccc(Cl)cc3)cc2Cl)O1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 17/20 0.68
THRB P10828 1/20 0.68
LMNA P02545 3/20 0.55
CYP51A1 Q16850 3/20 0.55
HSP90AA1 P07900 3/20 0.55
FYN P06241 2/20 0.55
NR1I2 O75469 2/20 0.55
CHRM2 P08172 2/20 0.55
ADRA2A P08913 2/20 0.55
TSHR P16473 2/20 0.55
ADRA2B P18089 2/20 0.55
SLC6A2 P23975 2/20 0.55
HTR2A P28223 2/20 0.55
SLC6A4 P31645 2/20 0.55
SLC6A3 Q01959 2/20 0.55
KCNH2 Q12809 2/20 0.55
PGR P06401 1/20 0.55
CHRM4 P08173 1/20 0.55
CHRM5 P08912 1/20 0.55
CHRM1 P11229 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Difenoconazole SCHEMBL29369735 1.00 CYP3A4 (0.68) CYP3A4THRBLMNACYP51A1HSP90AA1
Difenoconazole SCHEMBL29366085 1.00 CYP3A4 (0.68) CYP3A4THRBLMNACYP51A1HSP90AA1
Difenoconazole SCHEMBL15932554 1.00 CYP3A4 (0.68) CYP3A4THRBLMNACYP51A1HSP90AA1
Difenoconazole SCHEMBL29393627 1.00 CYP3A4 (0.68) CYP3A4THRBLMNACYP51A1HSP90AA1
Difenoconazole SCHEMBL29391271 1.00 CYP3A4 (0.68) CYP3A4THRBLMNACYP51A1HSP90AA1
Difenoconazole SCHEMBL22125 1.00 CYP3A4 (0.68) CYP3A4THRBLMNACYP51A1HSP90AA1
Difenoconazole SCHEMBL3015472 1.00 CYP3A4 (0.68) CYP3A4THRBLMNACYP51A1HSP90AA1
Difenoconazole SCHEMBL22126 1.00 CYP3A4 (0.68) CYP3A4THRBLMNACYP51A1HSP90AA1
Difenoconazole SCHEMBL15932941 1.00 CYP3A4 (0.68) CYP3A4THRBLMNACYP51A1HSP90AA1
Difenoconazole SCHEMBL20654517 1.00 CYP3A4 (0.68) CYP3A4THRBLMNACYP51A1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070131136-A1 Composition And Process For Coloring Wood OSMOSE, INC. (US) 2007-06-14 US claimed
EP-1269846-B1 Fungicidal mixtures SYNGENTA PARTICIPATIONS AG (CH) 2004-05-12 EP claimed
EP-1038442-B1 Fungicidal mixtures SYNGENTA PARTICIPATIONS AG (CH) 2003-06-04 EP claimed
EP-1269846-A1 Fungicidal mixtures Syngenta Participations AG (CH) 2003-01-02 EP claimed
US-6369090-B1 Fungicidal mixture BASF AKTIENGESELLSCHAFT (DE) 2002-04-09 US claimed
US-6225319-B1 I) DIFENOCONAZOLE; AND IIA) FLUQUINCONAZOLE OR IIB) 4,5-DIMETHYL-N-2-PROPENYL-2-(TRIMETHYLSILYL)-3-THIOPHENCARBOXA MID WHICH IS ESPECIALLY SUITABLE IN THE CONTROL AND PREVENTION OF DISEASE INFESTATION ON SEED. SYNGENTA CROP PROTECTION, INC. 2001-05-01 US claimed
EP-1038442-A2 Fungicidal mixtures Novartis AG (CH) 2000-09-27 EP claimed
EP-0663148-A2 Fungicidal compositions based on a 3,5-dichloroanilide like iprodione and a triazole compound RHONE-POULENC AGROCHIMIE (FR) 1995-07-19 EP claimed
US-12636810-B2 Wood preservative composition comprising 4,5-dichloro-2-octylisothiazol-3(2H)-one, a method treating a wood substrate therewith, and a wood product produced therefrom KOPPERS PERFORMANCE CHEMICALS, INC. (US) 2026-05-26 US disclosed
US-20260070256-A1 WOOD PRESERVATIVE COMPOSITION COMPRISING 4,5-DICHLORO-2-OCTYLISOTHIAZOL-3(2H)-ONE, A METHOD TREATING A WOOD SUBSTRATE THEREWITH, AND A WOOD PRODUCT PRODUCED THEREFROM KOPPERS PERFORMANCE CHEMICALS, INC. 2026-03-12 US disclosed
US-20250375917-A1 WOOD PRESERVATIVE COMPOSITION COMPRISING 4,5-DICHLORO-2-OCTYLISOTHIAZOL-3(2H)-ONE, A METHOD TREATING A WOOD SUBSTRATE THEREWITH, AND A WOOD PRODUCT PRODUCED THEREFROM KOPPERS PERFORMANCE CHEMICALS INC (US) 2025-12-11 US disclosed
US-12491658-B1 Wood preservative composition comprising 4,5-dichloro-2-octylisothiazol-3(2H)-one, a method treating a wood substrate therewith, and a wood product produced therefrom KOPPERS PERFORMANCE CHEMICALS, INC. (US) 2025-12-09 US disclosed
US-12370716-B2 Wood preservative composition comprising 4,5-dichloro-2-octylisothiazol-3(2H)-one, a method treating a wood substrate therewith, and a wood product produced therefrom KOPPERS PERFORMANCE CHEMICALS, INC. (US) 2025-07-29 US disclosed
US-20250196393-A1 WOOD PRESERVATIVE COMPOSITION COMPRISING 4,5-DICHLORO-2-OCTYLISOTHIAZOL-3(2H)-ONE, A METHOD TREATING A WOOD SUBSTRATE THEREWITH, AND A WOOD PRODUCT PRODUCED THEREFROM KOPPERS PERFORMANCE CHEMICALS INC (US) 2025-06-19 US disclosed
US-6225319-B1 I) DIFENOCONAZOLE; AND IIA) FLUQUINCONAZOLE OR IIB) 4,5-DIMETHYL-N-2-PROPENYL-2-(TRIMETHYLSILYL)-3-THIOPHENCARBOXA MID WHICH IS ESPECIALLY SUITABLE IN THE CONTROL AND PREVENTION OF DISEASE INFESTATION ON SEED. SYNGENTA CROP PROTECTION, INC. 2001-05-01 US disclosed
US-6225319-B1 I) DIFENOCONAZOLE; AND IIA) FLUQUINCONAZOLE OR IIB) 4,5-DIMETHYL-N-2-PROPENYL-2-(TRIMETHYLSILYL)-3-THIOPHENCARBOXA MID WHICH IS ESPECIALLY SUITABLE IN THE CONTROL AND PREVENTION OF DISEASE INFESTATION ON SEED. SYNGENTA CROP PROTECTION, INC. 2001-05-01 US disclosed
EP-1038442-A3 Fungicidal mixtures Novartis AG (CH) 2000-11-29 EP disclosed
EP-1038442-A2 Fungicidal mixtures Novartis AG (CH) 2000-09-27 EP disclosed
EP-1038442-A2 Fungicidal mixtures Novartis AG (CH) 2000-09-27 EP disclosed
EP-0976326-A1 Fungicidal composition containing a 1,2,3-tiadiazole derivative and its use NIHON NOHYAKU CO., LTD. (JP) 2000-02-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12636810-B2 Wood preservative composition comprising 4,5-dichloro-2-octylisothiazol-3(2H)-one, a method treating a wood substrate therewith, and a wood product produced therefrom NOTUM, ORMDL3, TEX264 CYP3A4 1277/4885THRB 4318/4885LMNA 1593/4885
US-20260070256-A1 WOOD PRESERVATIVE COMPOSITION COMPRISING 4,5-DICHLORO-2-OCTYLISOTHIAZOL-3(2H)-ONE, A METHOD TREATING A WOOD SUBSTRATE THEREWITH, AND A WOOD PRODUCT PRODUCED THEREFROM NOTUM, WEE2, WEE1 CYP3A4 522/4885THRB 3713/4885LMNA 2030/4885
US-20070131136-A1 Composition And Process For Coloring Wood BTD, MGAM, CYB5R3 CYP3A4 290/4885THRB 4846/4885LMNA 1415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.