Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 16/20 | 0.55 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3231865 | 0.99 | KCNH2 (0.54) | KCNH2SLC2A1TOP2A | |
| SCHEMBL3229915 | 0.86 | KCNH2 (0.55) | KCNH2SLC2A1TOP2A | |
| SCHEMBL3230788 | 0.86 | KCNH2 (0.63) | KCNH2SLC2A1 | |
| Hydrochloric Acid SCHEMBL3224143 | 0.86 | KCNH2 (0.62) | KCNH2SLC2A1 | |
| Hydrochloric Acid SCHEMBL3227002 | 0.86 | KCNH2 (0.62) | KCNH2SLC2A1 | |
| Hydrochloric Acid SCHEMBL3229449 | 0.86 | KCNH2 (0.54) | KCNH2SLC2A1TOP2A | |
| SCHEMBL3229489 | 0.84 | KCNH2 (0.62) | KCNH2SLC2A1TOP2A | |
| Hydrochloric Acid SCHEMBL3230434 | 0.84 | KCNH2 (0.61) | KCNH2SLC2A1TOP2A | |
| SCHEMBL3215054 | 0.80 | KCNH2 (0.67) | KCNH2SLC2A1TOP2A | |
| SCHEMBL3141859 | 0.79 | KCNH2 (0.69) | KCNH2TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056502-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-03-04 | — | — | US | claimed |
| US-20100056502-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-03-04 | — | — | US | disclosed |
| US-20100056502-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-03-04 | — | — | US | disclosed |
| WO-2008116815-A2 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056502-A1 | COMPOUNDS | NRDC, NACA, NAA50 | KCNH2 3105/4885SLC2A1 4172/4885TOP2A 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.