Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.75 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.64 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Pyrrolidone SCHEMBL5832885 | 1.00 | OR51E2 (0.75) | OR51E2CRBNFKBP5ALOX5KDM4E | |
| 2-Pyrrolidone SCHEMBL10474577 | 0.92 | — | — | |
| Caprolactam SCHEMBL28286059 | 0.91 | CRBN (0.73) | OR51E2CRBNFKBP5ALOX5KDM4E | |
| Hexane SCHEMBL6861569 | 0.91 | OR51E2 (0.68) | OR51E2CRBNFKBP5ALOX5KDM4E | |
| 2-Pyrrolidone SCHEMBL28327039 | 0.89 | OR51E2 (0.65) | OR51E2CRBNFKBP5ALOX5KDM4E | |
| Octane SCHEMBL5605719 | 0.89 | OR51E2 (0.65) | OR51E2CRBNFKBP5ALOX5KDM4E | |
| 2-Pyrrolidone SCHEMBL27585545 | 0.89 | OR51E2 (0.65) | OR51E2CRBNFKBP5ALOX5KDM4E | |
| 2-Pyrrolidone SCHEMBL28218276 | 0.88 | — | — | |
| 2-Pyrrolidone SCHEMBL5051625 | 0.88 | — | — | |
| 2-Pyrrolidone SCHEMBL29033368 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017053-A1 | SOLID EXCIPIENT COMPOSITIONS | ISP INVESTMENTS, INC. (US) | 2010-02-11 | — | — | WO | claimed |
| WO-2010017053-A1 | SOLID EXCIPIENT COMPOSITIONS | ISP INVESTMENTS, INC. (US) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010017053-A1 | SOLID EXCIPIENT COMPOSITIONS | ISP INVESTMENTS, INC. (US) | 2010-02-11 | — | — | WO | disclosed |