2-Pyrrolidone

2-Pyrrolidone

SCHEMBL5832885

CCCC.O=C1CCCN1

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.75
CRBN Q96SW2 4/20 0.64
FKBP5 Q13451 1/20 0.64
ALOX5 P09917 3/20 0.40
KDM4E B2RXH2 2/20 0.39
GAA P10253 1/20 0.39
POLB P06746 1/20 0.39
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TSHR P16473 1/20 0.33
PARP1 P09874 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Pyrrolidone SCHEMBL3225022 1.00 OR51E2 (0.75) OR51E2CRBNFKBP5ALOX5KDM4E
2-Pyrrolidone SCHEMBL10474577 0.92
Caprolactam SCHEMBL28286059 0.91 CRBN (0.73) OR51E2CRBNFKBP5ALOX5KDM4E
Hexane SCHEMBL6861569 0.91 OR51E2 (0.68) OR51E2CRBNFKBP5ALOX5KDM4E
2-Pyrrolidone SCHEMBL28327039 0.89 OR51E2 (0.65) OR51E2CRBNFKBP5ALOX5KDM4E
Octane SCHEMBL5605719 0.89 OR51E2 (0.65) OR51E2CRBNFKBP5ALOX5KDM4E
2-Pyrrolidone SCHEMBL27585545 0.89 OR51E2 (0.65) OR51E2CRBNFKBP5ALOX5KDM4E
2-Pyrrolidone SCHEMBL28218276 0.88
2-Pyrrolidone SCHEMBL5051625 0.88
2-Pyrrolidone SCHEMBL29033368 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112603998-B A compound preparation containing troxerutin for treating thrombi and its preparation method 黑龙江迪龙制药有限公司 2022-02-11 CN claimed
CN-112603998-A A compound preparation containing troxerutin for treating thrombi and its preparation method 黑龙江迪龙制药有限公司 2021-04-06 CN claimed
CN-110930862-A Novel anti-counterfeiting film 深圳市光科全息技术有限公司 2020-03-27 CN claimed
US-7141107-B2 Water color ink for ink jet recording SONY CORPORATION (JP) 2006-11-28 US claimed
US-20050178290-A1 Water color ink for ink jet recording SONY CORPORATION 2005-08-18 US claimed
CN-112603998-B A compound preparation containing troxerutin for treating thrombi and its preparation method 黑龙江迪龙制药有限公司 2022-02-11 CN disclosed
WO-2021129635-A1 SUSTAINED-RELEASE DRUG DELIVERY SYSTEM 南京清普生物科技有限公司 2021-07-01 WO disclosed
CN-112603998-A A compound preparation containing troxerutin for treating thrombi and its preparation method 黑龙江迪龙制药有限公司 2021-04-06 CN disclosed
CN-104876936-A Preparation of 2-hydroxy-1, 2-di-2-pyridylethanone and pyrazole class compound and application as medicine UNIV PLA 2ND MILITARY MEDICAL 2015-09-02 CN disclosed
US-7141107-B2 Water color ink for ink jet recording SONY CORPORATION (JP) 2006-11-28 US disclosed
US-7037362-B2 Water color ink for ink jet recording SONY CORPORATION (JP) 2006-05-02 US disclosed
US-20050178290-A1 Water color ink for ink jet recording SONY CORPORATION 2005-08-18 US disclosed
EP-1473340-A1 AQUEOUS INK FOR INK-JET RECORDING Sony Corporation (JP) 2004-11-03 EP disclosed
US-20040103815-A1 a water color ink with dry viscosity = 100 mPa*s or less, the dynamic surface tension at 10 ms = 45 mN/m or higher and the dynamic surface tension at 1000 ms is = 35 mN/m or less,: reduced bleeding and superior drying performance SONY CORPORATION (JP) 2004-06-03 US disclosed
US-6147178-A RUBBER COMPRISING DIENE-VINYL AROMATIC COPOLYMER BEARING QUATERNARY AMMONIUM GROUPS; TENSILE STRENGTH, WEAR RESISTANCE, HEAT RESISTANCE, IMPROVED AFFINITY FOR SILICA REINFORCEMENT NIPPON ZEON CO., LTD. (JP) 2000-11-14 US disclosed