Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL955096 | 0.78 | CES1 (0.56) | ALDH1A1GAAHDAC6 | |
| SCHEMBL4594374 | 0.77 | NAPRT (0.62) | CYP19A1ALDH1A1GAAKDM4E | |
| SCHEMBL13799024 | 0.77 | CA2 (0.56) | ALDH1A1KDM4ERAB9ANPC1CA2 | |
| SCHEMBL10520154 | 0.76 | CYP19A1 (0.42) | CYP19A1ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL10445460 | 0.75 | NPC1 (0.47) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10172435 | 0.75 | GAA (0.48) | ALDH1A1GAAKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL11470932 | 0.75 | CTBP2 (0.47) | ALDH1A1GAARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10750108 | 0.75 | CYP19A1 (0.52) | CYP19A1ALDH1A1GAAMAPTKDM4E | |
| SCHEMBL8040203 | 0.73 | CYP19A1 (0.50) | CYP19A1ALDH1A1GAAMAPTKDM4E | |
| SCHEMBL48554 | 0.73 | AKR1B1 (0.61) | CYP19A1ALDH1A1GAAMAPTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010009290-A1 | ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR INHIBITORS | WYETH (US) | 2010-01-21 | — | — | WO | disclosed |