Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21003285 | 0.86 | P2RX7 (0.41) | P2RX7 | |
| SCHEMBL29899522 | 0.86 | MTOR (0.39) | — | |
| SCHEMBL1833105 | 0.72 | MTOR (0.41) | — | |
| SCHEMBL3225920 | 0.71 | P2RX7 (0.35) | P2RX7 | |
| SCHEMBL30993160 | 0.65 | NR1H2 (0.39) | P2RX7 | |
| SCHEMBL1834283 | 0.63 | MTOR (0.38) | — | |
| SCHEMBL31598368 | 0.63 | MAPT (0.46) | — | |
| SCHEMBL16033728 | 0.62 | P2RX7 (0.57) | P2RX7 | |
| SCHEMBL16034797 | 0.62 | P2RX7 (0.59) | P2RX7 | |
| SCHEMBL16033934 | 0.62 | P2RX7 (0.57) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010014939-A1 | PYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | GENENTECH, INC. (US) | 2010-02-04 | — | — | WO | disclosed |