Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3216164 | 0.83 | MAPT (0.59) | MAPTPOLBTHRBALDH1A1HSP90AA1 | |
| SCHEMBL3263844 | 0.77 | MAPT (0.82) | MAPTPOLBTHRBALDH1A1HSP90AA1 | |
| SCHEMBL2011940 | 0.75 | BRD4 (0.39) | MAPTPOLBTHRBALDH1A1HSP90AA1 | |
| SCHEMBL2014758 | 0.75 | BRD4 (0.39) | MAPTPOLBTHRBALDH1A1HSP90AA1 | |
| SCHEMBL3260219 | 0.75 | MAPT (0.71) | MAPTPOLBTHRBALDH1A1HSP90AA1 | |
| SCHEMBL3264281 | 0.74 | MAPT (0.83) | MAPTPOLBTHRBALDH1A1HSP90AA1 | |
| SCHEMBL3262032 | 0.74 | MAPT (1.00) | MAPTPOLBTHRBALDH1A1HSP90AA1 | |
| SCHEMBL3226019 | 0.73 | MAPT (1.00) | MAPTPOLBTHRBALDH1A1HSP90AA1 | |
| SCHEMBL3264732 | 0.73 | MAPT (1.00) | MAPTPOLBTHRBALDH1A1HSP90AA1 | |
| SCHEMBL3218859 | 0.73 | MAPT (0.81) | MAPTPOLBTHRBALDH1A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003197-A1 | MORPHOLINE DERIVATIVES USED AS ANTIFUNGAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2010-01-14 | — | — | WO | disclosed |