Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3228977 | 0.94 | HSD11B1 (0.63) | HSD11B1HSD11B2 | |
| SCHEMBL7947530 | 0.94 | HSD11B1 (0.65) | HSD11B1HSD11B2 | |
| SCHEMBL3233551 | 0.94 | HSD11B1 (0.65) | HSD11B1HSD11B2 | |
| Trifluoroacetic Acid SCHEMBL3232037 | 0.92 | HSD11B1 (0.61) | HSD11B1HSD11B2 | |
| SCHEMBL7943138 | 0.92 | HSD11B1 (0.69) | HSD11B1HSD11B2 | |
| SCHEMBL3233475 | 0.91 | HSD11B1 (0.62) | HSD11B1HSD11B2 | |
| SCHEMBL3236961 | 0.91 | HSD11B1 (0.62) | HSD11B1HSD11B2 | |
| SCHEMBL3231341 | 0.91 | HSD11B1 (0.64) | HSD11B1HSD11B2 | |
| SCHEMBL3235675 | 0.90 | HSD11B1 (0.63) | HSD11B1HSD11B2 | |
| SCHEMBL3240581 | 0.90 | HSD11B1 (0.62) | HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011917-A1 | SEH AND 11β-HSD1 DUAL INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2010-01-28 | — | — | WO | claimed |
| WO-2010011917-A1 | SEH AND 11β-HSD1 DUAL INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2010-01-28 | — | — | WO | disclosed |
| WO-2010011917-A1 | SEH AND 11β-HSD1 DUAL INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2010-01-28 | — | — | WO | disclosed |