SCHEMBL3226515

SCHEMBL3226515

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(CC)C(=O)O[C@@H](CO)COP(=O)(O)OCCN

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 1/20 0.41
GPR55 Q9Y2T6 2/20 0.40
SELP P16109 1/20 0.40
PLA2G2C Q5R387 1/20 0.38
P2RY10 O00398 4/20 0.33
GPR34 Q9UPC5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13491206 1.00 S1PR1 (0.41) S1PR1GPR55SELPPLA2G2CP2RY10
SCHEMBL14780582 0.84 SELP (0.43) S1PR1GPR55SELPP2RY10GPR34
SCHEMBL30505157 0.81 S1PR1 (0.64) S1PR1GPR55SELP
SCHEMBL13491205 0.80 FABP3 (0.48) GPR55SELPP2RY10
SCHEMBL3224579 0.80 ALDH1A1 (0.46)
SCHEMBL31084781 0.80 S1PR1 (0.66) S1PR1GPR55SELPP2RY10
SCHEMBL31084780 0.80 S1PR1 (0.66) S1PR1GPR55SELPP2RY10
SCHEMBL31084782 0.80 S1PR1 (0.66) S1PR1GPR55SELPP2RY10
SCHEMBL30505170 0.80 S1PR1 (0.66) S1PR1GPR55SELPP2RY10
SCHEMBL30991473 0.80 S1PR1 (0.66) S1PR1GPR55SELPP2RY10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8399516-B2 Alpha-substituted omega-3 lipids that are activators or modulators of the peroxisome proliferators-activated receptor (PPAR) PRONOVA BIOPHARMA NORGE AS (NO) 2013-03-19 US claimed
US-20100035990-A1 ALPHA-SUBSTITUTED OMEGA-3 LIPIDS THAT ARE ACTIVATORS OR MODULATORS OF THE PEROXISOME PROLIFERATORS-ACTIVATED RECEPTOR (PPAR) PRONOVA BIOPHARMA NORGE AS (NO) 2010-02-11 US claimed
US-8399516-B2 Alpha-substituted omega-3 lipids that are activators or modulators of the peroxisome proliferators-activated receptor (PPAR) PRONOVA BIOPHARMA NORGE AS (NO) 2013-03-19 US disclosed
US-20100035990-A1 ALPHA-SUBSTITUTED OMEGA-3 LIPIDS THAT ARE ACTIVATORS OR MODULATORS OF THE PEROXISOME PROLIFERATORS-ACTIVATED RECEPTOR (PPAR) PRONOVA BIOPHARMA NORGE AS (NO) 2010-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100035990-A1 ALPHA-SUBSTITUTED OMEGA-3 LIPIDS THAT ARE ACTIVATORS OR MODULATORS OF THE PEROXISOME PROLIFERATORS-ACTIVATED RECEPTOR (PPAR) PPARG, PPARA, FFAR3 S1PR1 699/4885GPR55 611/4885SELP 2328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.