Itaconate

Itaconate

SCHEMBL3226816

C=C(CC(=O)O)C(=O)O.C=CC#N

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.65
HSD17B10 Q99714 1/20 0.65
TSHR P16473 3/20 0.39
ALDH1A1 P00352 2/20 0.39
LDHA P00338 1/20 0.33
SRR Q9GZT4 1/20 0.33
KDM4E B2RXH2 1/20 0.32
TET2 Q6N021 3/20 0.31
TET3 O43151 1/20 0.31
TET1 Q8NFU7 1/20 0.31
GRIK1 P39086 1/20 0.30
GRIK2 Q13002 1/20 0.30
GRM1 Q13255 1/20 0.30
GRM2 Q14416 1/20 0.30
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Itaconate SCHEMBL27767716 1.00 ALOX15 (0.65) ALOX15HSD17B10TSHRALDH1A1LDHA
Itaconate SCHEMBL27817710 0.98 ALOX15 (0.63) ALOX15HSD17B10TSHRALDH1A1LDHA
Itaconate SCHEMBL27971639 0.98 ALOX15 (0.63) ALOX15HSD17B10TSHRALDH1A1LDHA
Itaconate SCHEMBL27796637 0.98 ALOX15 (0.63) ALOX15HSD17B10TSHRALDH1A1LDHA
Itaconate SCHEMBL27796632 0.98 ALOX15 (0.63) ALOX15HSD17B10TSHRALDH1A1LDHA
Itaconate SCHEMBL28375691 0.98 ALOX15 (0.63) ALOX15HSD17B10TSHRALDH1A1LDHA
Itaconate SCHEMBL17073956 0.96 ALOX15 (0.61) ALOX15HSD17B10TSHRALDH1A1LDHA
Itaconate SCHEMBL6369503 0.94 ALOX15 (0.59) ALOX15HSD17B10TSHRALDH1A1
Itaconate SCHEMBL11863864 0.94 ALOX15 (0.59) ALOX15HSD17B10TSHRALDH1A1
Itaconate SCHEMBL28188939 0.94 ALOX15 (0.77) ALOX15HSD17B10TSHRALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024015971-A2 MULTILAYER BATTERY SEPARATOR COMPRISING A MICROPOROUS POLYMER LAYER SEPION TECHNOLOGIES, INC. (US) 2024-01-18 WO claimed
CN-117199311-A Sodium vanadium fluorophosphate/carbon nanofiber composite material and preparation method and application thereof 江苏正力新能电池技术有限公司 2023-12-08 CN claimed
CN-115928238-A High-uniformity polyacrylonitrile nascent fiber and preparation method thereof 中国石油化工股份有限公司 2023-04-07 CN claimed
CN-112881334-B Method for detecting itaconic acid content in poly (acrylonitrile-itaconic acid) 山东非金属材料研究所 2022-08-26 CN claimed
CN-111599607-B Hollow carbon nanofiber-CoS2Electrode material of super capacitor and preparation method thereof 广东海之源新材料科技有限公司 2022-05-06 CN claimed
CN-112881334-A Method for detecting itaconic acid content in poly (acrylonitrile-itaconic acid) 山东非金属材料研究所 2021-06-01 CN claimed
CN-111599607-A Hollow carbon nanofiber-CoS2Electrode material of super capacitor and preparation method thereof 邓新峰 2020-08-28 CN claimed
CN-109796715-A A kind of energy conservation and environmental protection agricultural green house of vegetables film and preparation method thereof 张炜平 2019-05-24 CN claimed
CN-109487369-A A kind of Khotan jade fiber and preparation method thereof 肖晖 2019-03-19 CN claimed
CN-106894105-A A kind of porous polypropylene nitrile fiber and its preparation method and application 中国科学院宁波材料技术与工程研究所 2017-06-27 CN claimed
CN-104028238-A Preparation method of arsenic removal adsorbent based on polyacrylonitrile-itaconic acid UNIV LUDONG 2014-09-10 CN claimed
CN-103603089-A Radiation shielding non-woven fabric and preparation method thereof UNIV HONG KONG POLYTECHNIC 2014-02-26 CN claimed
CN-103556308-A Radiation shielding fiber and preparation method thereof UNIV HONG KONG POLYTECHNIC 2014-02-05 CN claimed
CN-102838708-A Preparation method of acrylonitrile-itaconic acid bipolymer spinning solution USTC UNIV SCIENCE TECH CN 2012-12-26 CN claimed
CN-101891930-B Carbon nano tube-containing sulfur-based composite cathode material and preparation method thereof UNIV SHANGHAI JIAOTONG 2012-01-04 CN claimed
CN-101891930-A Carbon nano tube-containing sulfur-based composite cathode material and preparation method thereof UNIV SHANGHAI JIAOTONG 2010-11-24 CN claimed
US-20050100501-A1 Macroscopic fiber comprising single-wall carbon nanotubes and acrylonitrile-based polymer and process for making the same GEORGIA TECH RESEARCH CORPORATION 2005-05-12 US claimed
US-6852410-B2 Macroscopic fiber comprising single-wall carbon nanotubes and acrylonitrile-based polymer and process for making the same GEORGIA TECH RESEARCH CORPORATION (US) 2005-02-08 US claimed
US-20040180201-A1 Macroscopic fiber comprising single-wall carbon nanotubes and acrylonitrile-based polymer and process for making the same GEORGIA TECH RESEARCH CORPORATION 2004-09-16 US claimed
US-4199491-A Polyolefin resin composition IDEMITSU KOSAN COMPANY LIMITED (JP) 1980-04-22 US claimed