Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 20/20 | 0.63 |
| ▸ | BACE1 | P56817 | 20/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL309085 | 0.89 | CTSD (0.58) | CTSDBACE1 | |
| SCHEMBL4260201 | 0.87 | CTSD (0.61) | CTSDBACE1CYP3A4 | |
| SCHEMBL4255806 | 0.85 | CTSD (0.49) | CTSDBACE1CYP3A4 | |
| SCHEMBL3222172 | 0.84 | CTSD (0.54) | CTSDBACE1CYP3A4 | |
| SCHEMBL309571 | 0.84 | CTSD (0.48) | CTSDBACE1CYP3A4 | |
| SCHEMBL309701 | 0.83 | CTSD (0.61) | CTSDBACE1CYP3A4 | |
| SCHEMBL4256055 | 0.83 | CTSD (0.59) | CTSDBACE1CYP3A4 | |
| SCHEMBL310220 | 0.82 | CTSD (0.46) | CTSDBACE1CYP3A4 | |
| SCHEMBL4257146 | 0.82 | CTSD (0.46) | CTSDBACE1CYP3A4 | |
| SCHEMBL308670 | 0.82 | BACE1 (0.57) | CTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056490-A1 | Cyclic sulfones with aminobenzyl substitution useful as BACE inhibitors | NOVARTIS AG (CH) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056490-A1 | Cyclic sulfones with aminobenzyl substitution useful as BACE inhibitors | BACE2, BACE1, APP | CTSD 33/4885BACE1 2/4885CYP3A4 816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.