Urea

Urea

SCHEMBL3227022

C#C.NC(N)=O.NC(N)=O

nearest known ligand 0.75

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.75
ALDH1A1 P00352 4/20 0.75
TDP1 Q9NUW8 3/20 0.75
OR51E2 Q9H255 1/20 0.75
ACHE P22303 1/20 0.50
BLM P54132 4/20 0.46
PMP22 Q01453 3/20 0.46
ALOX15 P16050 2/20 0.46
LDHA P00338 2/20 0.42
LDHB P07195 1/20 0.42
CYP3A4 P08684 3/20 0.39
TSHR P16473 3/20 0.39
NFKB1 P19838 2/20 0.39
HPGD P15428 2/20 0.39
HSD17B10 Q99714 2/20 0.39
CYP1A2 P05177 2/20 0.39
THPO P40225 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
EHMT2 Q96KQ7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL669523 1.00
Urea SCHEMBL11134805 0.89
Urea SCHEMBL4446177 0.89
Urea SCHEMBL8560069 0.87 LMNA (1.00) LMNAALDH1A1TDP1OR51E2ACHE
Urea SCHEMBL8434002 0.87 LMNA (1.00) LMNAALDH1A1TDP1OR51E2ACHE
Urea SCHEMBL411583 0.87
Urea SCHEMBL7756359 0.87 LMNA (1.00) LMNAALDH1A1TDP1OR51E2ACHE
Urea SCHEMBL20641124 0.87 LMNA (1.00) LMNAALDH1A1TDP1OR51E2ACHE
Urea C 13 SCHEMBL12476878 0.87
Urea SCHEMBL8436158 0.87 LMNA (1.00) LMNAALDH1A1TDP1OR51E2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101460534-B Microcapsules comprising an acetyleneurea-polyurea polymer and controlled release formulations thereof GAT MICROENCAPSULATION AG 2013-10-23 CN disclosed
US-20100050514-A1 PLANT SUBSTRATE BASED ON OPEN-CELLED MELAMINE/FORMALDEHYDE FOAM BASF SE (DE) 2010-03-04 US disclosed
CN-101460534-A Microcapsules comprising an acetyleneurea-polyurea polymer and controlled release formulations thereof GAT MICROENCAPSULATION AG (AT) 2009-06-17 CN disclosed
EP-1318126-A1 Nitrogen containing long-term release fertilizer COMPO Gesellschaft mbH & Co. KG (DE) 2003-06-11 EP disclosed
EP-0199262-B1 FLUORINATED BENZYL TRIAZOLE COMPOUNDS CIBA-GEIGY AG (CH) 1991-02-27 EP disclosed
EP-0199262-A2 Fluorinated benzyl triazole compounds CIBA-GEIGY AG (CH) 1986-10-29 EP disclosed