⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1294254 | 0.67 | — | — | |
| SCHEMBL669397 | 0.67 | — | — | |
| SCHEMBL5116420 | 0.67 | — | — | |
| SCHEMBL20168627 | 0.67 | — | — | |
| SCHEMBL4060689 | 0.65 | — | — | |
| SCHEMBL38028 | 0.59 | — | — | |
| SCHEMBL234303 | 0.59 | — | — | |
| SCHEMBL258389 | 0.59 | — | — | |
| SCHEMBL229347 | 0.59 | — | — | |
| SCHEMBL38382 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 318 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9458084-B2 | Manufacture of 1-substituted methylidene compounds | SOLVAY SA (BE) | 2016-10-04 | — | — | US | claimed |
| US-20150126765-A1 | MANUFACTURE OF 1-SUBSTITUTED METHYLIDENE COMPOUNDS | SOLVAY SA (BE) | 2015-05-07 | — | — | US | claimed |
| EP-2850055-A1 | MANUFACTURE OF 1-SUBSTITUTED METHYLIDENE COMPOUNDS | Solvay SA (BE) | 2015-03-25 | — | — | EP | claimed |
| EP-2671873-A1 | Method for the cyclization of hydrazinoacrylic acid derivatives | SOLVAY SA (BE) | 2013-12-11 | — | — | EP | claimed |
| WO-2013171102-A1 | MANUFACTURE OF 1-SUBSTITUTED METHYLIDENE COMPOUNDS | SOLVAY SA (BE) | 2013-11-21 | — | — | WO | claimed |
| WO-2004085400-A1 | SUBSTITUTED PYRI(MI)DIN(THIO)CARBOXAMIDES USED AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2004-10-07 | — | — | WO | claimed |
| WO-2001047917-A1 | SUBSTITUTED THIENYLALKYLAMINO-1,3,5-TRIAZINES FOR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-05 | — | — | WO | claimed |
| WO-2001010853-A1 | SUBSTITUTED 2-IMINO-THIAZOLINES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-15 | — | — | WO | claimed |
| EP-0392241-A1 | Substituted 1-Arylpyrazols | BAYER AG (DE) | 1990-10-17 | — | — | EP | claimed |
| US-4460584-A | GUANIDINE DERIVATIVES, ANTISECRETORY AGENT | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-07-17 | — | — | US | claimed |
| US-4104377-A | Disubstituted-O-(1-fluoro-2-halogenoethyl)-phosphoric(phosphonic) acid esters, and method of combating insects | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | claimed |
| US-11976075-B2 | Inhibitors of the MYST family of lysine acetyl transferases | Isosterix, Inc. | 2024-05-07 | — | — | US | disclosed |
| WO-2024059317-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | BRIDGENE BIOSCIENCES, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| US-20230416260-A1 | Inhibitors of the MYST Family of Lysine Acetyl Transferases | Isosterix, Inc. | 2023-12-28 | — | — | US | disclosed |
| CN-115215871-B | Organic compound, and organic electroluminescent device and electronic device using same | 陕西莱特迈思光电材料有限公司 | 2023-10-31 | — | — | CN | disclosed |
| EP-0212353-A2 | 1-Aryl-5-hydrazino-pyrazoles | BAYER AG (DE) | 1987-03-04 | — | — | EP | disclosed |
| US-4502994-A | Enantiomeric synthesis of 3-amino-4-carbamoyloxymethyl-2-azetidonone-1-sulfate | HOFFMANN-LA ROCHE INC. (US) | 1985-03-05 | — | — | US | disclosed |
| EP-0111326-A1 | Process for the manufacture of chiral azetidinones | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-06-20 | — | — | EP | disclosed |
| US-4104377-A | Disubstituted-O-(1-fluoro-2-halogenoethyl)-phosphoric(phosphonic) acid esters, and method of combating insects | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |
| US-4036628-A | THIOCARBAMATES, PHOSPHATES, PHOSPHONATES | STAUFFER CHEMICAL COMPANY (US) | 1977-07-19 | — | — | US | disclosed |