Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | EBP | Q15125 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18725903 | 0.87 | MEN1 (0.44) | KMT2AMEN1POLBKDM4ESIGMAR1 | |
| SCHEMBL18725902 | 0.87 | MEN1 (0.44) | KMT2AMEN1POLBKDM4ESIGMAR1 | |
| SCHEMBL3271994 | 0.75 | KMT2A (0.40) | KMT2AMEN1POLBMCHR1EBP | |
| SCHEMBL4702727 | 0.74 | — | — | |
| SCHEMBL18725915 | 0.73 | BLM (0.33) | KMT2AMEN1POLBBLM | |
| SCHEMBL18725908 | 0.73 | BLM (0.33) | KMT2AMEN1POLBBLM | |
| SCHEMBL5322174 | 0.71 | MEN1 (0.50) | KMT2AMEN1POLBKDM4EMCHR1 | |
| SCHEMBL9342491 | 0.70 | — | — | |
| SCHEMBL21277496 | 0.70 | MEN1 (0.35) | KMT2AMEN1POLBKDM4ECYP1A2 | |
| SCHEMBL1123426 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3104847-B1 | NOVEL USE OF SIGMA-1 RECEPTOR AGONIST COMPOUNDS | MTA TAMOGATOTT KUTATOCSOPORTOK IRODAJA (HU) | 2020-11-11 | — | — | EP | claimed |
| EP-1077240-B1 | Aqueous dispersion for chemical mechanical polishing | JSR CORP (JP) | 2006-11-08 | — | — | EP | claimed |
| EP-2249779-A2 | COSMETIC COMPOSITION COMPRISING A CATIONIC SURFACTANT COMPOUND, NOVEL COMPOUNDS, USE AS CONDITIONER AND COSMETIC TREATMENT METHOD | L'Oréal (FR) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009101322-A2 | COSMETIC COMPOSITION COMPRISING A CATIONIC SURFACTANT COMPOUND, NOVEL COMPOUNDS, USE AS CONDITIONER AND COSMETIC TREATMENT METHOD | L'OREAL (FR) | 2009-08-20 | — | — | WO | disclosed |